Seahorse Protein Hydrolysate Ameliorates Proinflammatory Mediators and Cartilage Degradation on Posttraumatic Osteoarthritis with an Obesity Rat Model

Osteoarthritis (OA) is one of the age-related diseases and is highly present on the knees. Obesity and mechanical injuries as a risk factor of OA are attributed to cartilage disintegration, joint loading, and inflammation. This study is aimed at investigating the effects of seahorse protein hydrolys...

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Veröffentlicht in:	BioMed research international 2022-04, Vol.2022, p.4117520-11
Hauptverfasser:	Sudirman, Sabri, Tseng, Po-Sheng, Chen, Chun-Kai, Tsou, David, Kong, Zwe-Ling
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Age related diseases Animals Anterior cruciate ligament Arthritis Biomedical materials Body weight Care and treatment Cartilage Cartilage (articular) Cartilage diseases Cartilage, Articular - metabolism Collagen (type II) Collagenase 3 Complications and side effects Degradation Disease Models, Animal Disintegration Enzymes Genetic aspects Glutathione Glutathione peroxidase Health aspects Health risks High fat diet Hippocampus hippocampus Hydrolysates Inflammation Joints (anatomy) Kinases Knee Ligaments Male Matrix metalloproteinase Matrix metalloproteinases Measuring instruments Metalloproteinase Nutrition research Obesity Obesity - complications Obesity - metabolism Osteoarthritis Osteoarthritis - metabolism Pain Pain - metabolism Patient outcomes Peroxidase Protein hydrolysates Protein Hydrolysates - metabolism Proteins Proteoglycans Rats Rats, Sprague-Dawley Risk analysis Risk factors Sea horses Skin Smegmamorpha Superoxide dismutase Surgery Tumor necrosis factor-TNF
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