Synthesis of Schiff and Mannich bases of new s -triazole derivatives and their potential applications for removal of heavy metals from aqueous solution and as antimicrobial agents

An efficient, simple, and one-pot double Mannich reaction was performed for the synthesis of cyclized 2-methyl-6-substituted-6,7-dihydro-5 -triazolo[5,1- ]-1,3,5-thiadiazines a reaction of 5-methyl-1 -triazole-3-thiol (1) with formaldehyde and primary aliphatic amines in ethanol at room temperature,...

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