Serum Ammonia in Cirrhosis: Clinical Impact of Hyperammonemia, Utility of Testing, and National Testing Trends

Ammonia is central to the pathophysiology of hepatic encephalopathy (HE) in cirrhosis. Serum ammonia levels have prognostic value and have been implicated in sarcopenia, hepatotoxicity, and immune dysfunction. Studies indicate that clinicians frequently order serum ammonia levels in decompensated ci...

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Veröffentlicht in:	Clinical therapeutics 2022-03, Vol.44 (3), p.e45-e57
Hauptverfasser:	Deutsch-Link, Sasha, Moon, Andrew M., Jiang, Yue, Barritt, A. Sidney, Tapper, Elliot B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Amino acids Ammonia Ammonia - analysis Animal cognition Blood-brain barrier Cirrhosis Coma Dendritic cells Edema Electronic health records Electronic medical records Enzymes Hepatic encephalopathy Hepatic Encephalopathy - diagnosis Hepatic Encephalopathy - epidemiology Hepatic Encephalopathy - etiology Hepatotoxicity Homeostasis Humans Hyperammonemia Hyperammonemia - diagnosis Hypertension Kidneys Laboratories Literature reviews Liver cirrhosis Liver Cirrhosis - diagnosis Liver disease Liver diseases Metabolism Musculoskeletal system Neurotoxicity Neutrophils Oxidative stress Pathophysiology Protein synthesis Proteins Sarcopenia Trends
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