Implant-based dental rehabilitation in head and neck cancer patients after maxillofacial reconstruction with a free vascularized fibula flap: the effect on health-related quality of life
Purpose To evaluate the effect of implant-based dental rehabilitation (IDR) on health-related quality of life (HRQoL) in head and neck cancer (HNC) patients after reconstruction with a free vascularized fibula flap (FFF). Methods Eligible patients were identified by retrospectively reviewing the med...
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Veröffentlicht in: | Supportive care in cancer 2022-06, Vol.30 (6), p.5411-5420 |
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creator | Lodders, Johannes N. van Baar, Gustaaf J. C. Vergeer, Marije R. Jansen, Femke Schulten, Engelbert A. J. M. Lissenberg-Witte, Birgit I. Verdonck-de Leeuw, Irma M. Forouzanfar, Tymour Leusink, Frank K. J. |
description | Purpose
To evaluate the effect of implant-based dental rehabilitation (IDR) on health-related quality of life (HRQoL) in head and neck cancer (HNC) patients after reconstruction with a free vascularized fibula flap (FFF).
Methods
Eligible patients were identified by retrospectively reviewing the medical records of patients treated in Amsterdam UMC-VUmc. HRQoL data were used from OncoQuest, a hospital-based system to collect patient-reported outcome measures in routine care. Data were used of the EORTC QLQ-C30 and QLQ-H&N 35 before FFF reconstruction (T
0
) and after completing IDR (T
1
). Data were statistically analysed with the chi-square test, independent samples
t
test and linear mixed models.
Results
Out of 96 patients with maxillofacial FFF reconstruction between January 2006 and October 2017, 57 patients (19 with and 38 without IDR) had HRQoL data at T
0
and T
1
. In the cross-sectional analysis, patients with IDR scored significantly better at T
0
and T
1
on several EORTC domains compared to the patients without IDR. Weight loss was significantly different in the within-subject analysis between T
0
and T
1
for patients with IDR (
p
= 0.011). However, there were no significant differences in the mean changes of all the EORTC QLQ-C30 and EORTC QLQ-H&N35 scores between the defined timepoints for patients with IDR compared to those without.
Conclusions
In this study, no differences were found in the course of HRQoL in HNC patients who had undergone IDR after maxillofacial FFF reconstruction, compared to those who had not. Patients should be preoperatively informed to have realistic expectations regarding the outcome of IDR. |
doi_str_mv | 10.1007/s00520-022-06944-4 |
format | Article |
fullrecord | <record><control><sourceid>gale_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9046363</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A701892187</galeid><sourcerecordid>A701892187</sourcerecordid><originalsourceid>FETCH-LOGICAL-c541t-ffa32ebbe7712ed70cb407b2285f1d729591918930a4079c0a88f287b0b177833</originalsourceid><addsrcrecordid>eNp9Uk1v1DAQjRCIlsIf4IAsceGSYjvxOuGAVFV8VKrEBc7WxBlvXJxkazuF8tP4dczulpYihHyI7XnvTd74FcVzwY8F5_p14lxJXnIpS75q67qsHxSHoq6qUldV-7A45G0tyrpS6qB4ktIF50JrJR8XB5WSbaOFOix-no2bAFMuO0jYsx6nDIFFHKDzwWfIfp6Yn9iA0DOYejah_cosTBYj21CZCImBy3Qc4bsPYXZg_U7DzlPKcbE7jW8-DwyYi4jsCpJdAkT_g1o639GeuQCbNywPyNA5tJnNu6YhD2XEAJmQlwvQL12z2bHgHT4tHjkICZ_dfI-KL-_ffT79WJ5_-nB2enJeWlWLXDoHlcSuQ62FxF5z29Vcd1I2yoley1a1ohVNW3Gg-9ZyaBonG93xjsbVVNVR8Xavu1m6EXtLjiMEs4l-hHhtZvDmfmXyg1nPV6bl9apabQVe3QjE-XLBlM3ok8VAc8d5SUauanpPrrgi6Mu_oBfzEieyRyilWqmlau5Qawho_ORm6mu3ouZEc_IiRaMJdfwPFK0eR09vg87T_T2C3BNsnFOK6G49Cm62iTP7xBlKnNklztREevHndG4pvyNGgGoPSFSa1hjvLP1H9heuR-PN</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2655927258</pqid></control><display><type>article</type><title>Implant-based dental rehabilitation in head and neck cancer patients after maxillofacial reconstruction with a free vascularized fibula flap: the effect on health-related quality of life</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>Lodders, Johannes N. ; van Baar, Gustaaf J. C. ; Vergeer, Marije R. ; Jansen, Femke ; Schulten, Engelbert A. J. M. ; Lissenberg-Witte, Birgit I. ; Verdonck-de Leeuw, Irma M. ; Forouzanfar, Tymour ; Leusink, Frank K. J.</creator><creatorcontrib>Lodders, Johannes N. ; van Baar, Gustaaf J. C. ; Vergeer, Marije R. ; Jansen, Femke ; Schulten, Engelbert A. J. M. ; Lissenberg-Witte, Birgit I. ; Verdonck-de Leeuw, Irma M. ; Forouzanfar, Tymour ; Leusink, Frank K. J.</creatorcontrib><description>Purpose
To evaluate the effect of implant-based dental rehabilitation (IDR) on health-related quality of life (HRQoL) in head and neck cancer (HNC) patients after reconstruction with a free vascularized fibula flap (FFF).
Methods
Eligible patients were identified by retrospectively reviewing the medical records of patients treated in Amsterdam UMC-VUmc. HRQoL data were used from OncoQuest, a hospital-based system to collect patient-reported outcome measures in routine care. Data were used of the EORTC QLQ-C30 and QLQ-H&N 35 before FFF reconstruction (T
0
) and after completing IDR (T
1
). Data were statistically analysed with the chi-square test, independent samples
t
test and linear mixed models.
Results
Out of 96 patients with maxillofacial FFF reconstruction between January 2006 and October 2017, 57 patients (19 with and 38 without IDR) had HRQoL data at T
0
and T
1
. In the cross-sectional analysis, patients with IDR scored significantly better at T
0
and T
1
on several EORTC domains compared to the patients without IDR. Weight loss was significantly different in the within-subject analysis between T
0
and T
1
for patients with IDR (
p
= 0.011). However, there were no significant differences in the mean changes of all the EORTC QLQ-C30 and EORTC QLQ-H&N35 scores between the defined timepoints for patients with IDR compared to those without.
Conclusions
In this study, no differences were found in the course of HRQoL in HNC patients who had undergone IDR after maxillofacial FFF reconstruction, compared to those who had not. Patients should be preoperatively informed to have realistic expectations regarding the outcome of IDR.</description><identifier>ISSN: 0941-4355</identifier><identifier>EISSN: 1433-7339</identifier><identifier>DOI: 10.1007/s00520-022-06944-4</identifier><identifier>PMID: 35298715</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Analysis ; Cancer patients ; Cancer surgery ; Care and treatment ; Cross-Sectional Studies ; Dental implants ; Fibula ; Head & neck cancer ; Head and neck cancer ; Head and Neck Neoplasms - surgery ; Health aspects ; Humans ; Implant dentures ; Maxillofacial surgery ; Medical records ; Medicine ; Medicine & Public Health ; Nursing ; Nursing Research ; Oncology ; Original ; Original Article ; Pain Medicine ; Quality of Life ; Reconstructive surgery ; Rehabilitation Medicine ; Retrospective Studies ; Surgical outcomes</subject><ispartof>Supportive care in cancer, 2022-06, Vol.30 (6), p.5411-5420</ispartof><rights>The Author(s) 2022</rights><rights>2022. The Author(s).</rights><rights>COPYRIGHT 2022 Springer</rights><rights>The Author(s) 2022. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c541t-ffa32ebbe7712ed70cb407b2285f1d729591918930a4079c0a88f287b0b177833</citedby><cites>FETCH-LOGICAL-c541t-ffa32ebbe7712ed70cb407b2285f1d729591918930a4079c0a88f287b0b177833</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00520-022-06944-4$$EPDF$$P50$$Gspringer$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00520-022-06944-4$$EHTML$$P50$$Gspringer$$Hfree_for_read</linktohtml><link.rule.ids>230,314,780,784,885,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35298715$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lodders, Johannes N.</creatorcontrib><creatorcontrib>van Baar, Gustaaf J. C.</creatorcontrib><creatorcontrib>Vergeer, Marije R.</creatorcontrib><creatorcontrib>Jansen, Femke</creatorcontrib><creatorcontrib>Schulten, Engelbert A. J. M.</creatorcontrib><creatorcontrib>Lissenberg-Witte, Birgit I.</creatorcontrib><creatorcontrib>Verdonck-de Leeuw, Irma M.</creatorcontrib><creatorcontrib>Forouzanfar, Tymour</creatorcontrib><creatorcontrib>Leusink, Frank K. J.</creatorcontrib><title>Implant-based dental rehabilitation in head and neck cancer patients after maxillofacial reconstruction with a free vascularized fibula flap: the effect on health-related quality of life</title><title>Supportive care in cancer</title><addtitle>Support Care Cancer</addtitle><addtitle>Support Care Cancer</addtitle><description>Purpose
To evaluate the effect of implant-based dental rehabilitation (IDR) on health-related quality of life (HRQoL) in head and neck cancer (HNC) patients after reconstruction with a free vascularized fibula flap (FFF).
Methods
Eligible patients were identified by retrospectively reviewing the medical records of patients treated in Amsterdam UMC-VUmc. HRQoL data were used from OncoQuest, a hospital-based system to collect patient-reported outcome measures in routine care. Data were used of the EORTC QLQ-C30 and QLQ-H&N 35 before FFF reconstruction (T
0
) and after completing IDR (T
1
). Data were statistically analysed with the chi-square test, independent samples
t
test and linear mixed models.
Results
Out of 96 patients with maxillofacial FFF reconstruction between January 2006 and October 2017, 57 patients (19 with and 38 without IDR) had HRQoL data at T
0
and T
1
. In the cross-sectional analysis, patients with IDR scored significantly better at T
0
and T
1
on several EORTC domains compared to the patients without IDR. Weight loss was significantly different in the within-subject analysis between T
0
and T
1
for patients with IDR (
p
= 0.011). However, there were no significant differences in the mean changes of all the EORTC QLQ-C30 and EORTC QLQ-H&N35 scores between the defined timepoints for patients with IDR compared to those without.
Conclusions
In this study, no differences were found in the course of HRQoL in HNC patients who had undergone IDR after maxillofacial FFF reconstruction, compared to those who had not. Patients should be preoperatively informed to have realistic expectations regarding the outcome of IDR.</description><subject>Analysis</subject><subject>Cancer patients</subject><subject>Cancer surgery</subject><subject>Care and treatment</subject><subject>Cross-Sectional Studies</subject><subject>Dental implants</subject><subject>Fibula</subject><subject>Head & neck cancer</subject><subject>Head and neck cancer</subject><subject>Head and Neck Neoplasms - surgery</subject><subject>Health aspects</subject><subject>Humans</subject><subject>Implant dentures</subject><subject>Maxillofacial surgery</subject><subject>Medical records</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Nursing</subject><subject>Nursing Research</subject><subject>Oncology</subject><subject>Original</subject><subject>Original Article</subject><subject>Pain Medicine</subject><subject>Quality of Life</subject><subject>Reconstructive surgery</subject><subject>Rehabilitation Medicine</subject><subject>Retrospective Studies</subject><subject>Surgical outcomes</subject><issn>0941-4355</issn><issn>1433-7339</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp9Uk1v1DAQjRCIlsIf4IAsceGSYjvxOuGAVFV8VKrEBc7WxBlvXJxkazuF8tP4dczulpYihHyI7XnvTd74FcVzwY8F5_p14lxJXnIpS75q67qsHxSHoq6qUldV-7A45G0tyrpS6qB4ktIF50JrJR8XB5WSbaOFOix-no2bAFMuO0jYsx6nDIFFHKDzwWfIfp6Yn9iA0DOYejah_cosTBYj21CZCImBy3Qc4bsPYXZg_U7DzlPKcbE7jW8-DwyYi4jsCpJdAkT_g1o639GeuQCbNywPyNA5tJnNu6YhD2XEAJmQlwvQL12z2bHgHT4tHjkICZ_dfI-KL-_ffT79WJ5_-nB2enJeWlWLXDoHlcSuQ62FxF5z29Vcd1I2yoley1a1ohVNW3Gg-9ZyaBonG93xjsbVVNVR8Xavu1m6EXtLjiMEs4l-hHhtZvDmfmXyg1nPV6bl9apabQVe3QjE-XLBlM3ok8VAc8d5SUauanpPrrgi6Mu_oBfzEieyRyilWqmlau5Qawho_ORm6mu3ouZEc_IiRaMJdfwPFK0eR09vg87T_T2C3BNsnFOK6G49Cm62iTP7xBlKnNklztREevHndG4pvyNGgGoPSFSa1hjvLP1H9heuR-PN</recordid><startdate>202206</startdate><enddate>202206</enddate><creator>Lodders, Johannes N.</creator><creator>van Baar, Gustaaf J. C.</creator><creator>Vergeer, Marije R.</creator><creator>Jansen, Femke</creator><creator>Schulten, Engelbert A. J. M.</creator><creator>Lissenberg-Witte, Birgit I.</creator><creator>Verdonck-de Leeuw, Irma M.</creator><creator>Forouzanfar, Tymour</creator><creator>Leusink, Frank K. J.</creator><general>Springer Berlin Heidelberg</general><general>Springer</general><general>Springer Nature B.V</general><scope>C6C</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0-V</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88J</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HEHIP</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2R</scope><scope>M2S</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>202206</creationdate><title>Implant-based dental rehabilitation in head and neck cancer patients after maxillofacial reconstruction with a free vascularized fibula flap: the effect on health-related quality of life</title><author>Lodders, Johannes N. ; van Baar, Gustaaf J. C. ; Vergeer, Marije R. ; Jansen, Femke ; Schulten, Engelbert A. J. M. ; Lissenberg-Witte, Birgit I. ; Verdonck-de Leeuw, Irma M. ; Forouzanfar, Tymour ; Leusink, Frank K. J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c541t-ffa32ebbe7712ed70cb407b2285f1d729591918930a4079c0a88f287b0b177833</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Analysis</topic><topic>Cancer patients</topic><topic>Cancer surgery</topic><topic>Care and treatment</topic><topic>Cross-Sectional Studies</topic><topic>Dental implants</topic><topic>Fibula</topic><topic>Head & neck cancer</topic><topic>Head and neck cancer</topic><topic>Head and Neck Neoplasms - surgery</topic><topic>Health aspects</topic><topic>Humans</topic><topic>Implant dentures</topic><topic>Maxillofacial surgery</topic><topic>Medical records</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Nursing</topic><topic>Nursing Research</topic><topic>Oncology</topic><topic>Original</topic><topic>Original Article</topic><topic>Pain Medicine</topic><topic>Quality of Life</topic><topic>Reconstructive surgery</topic><topic>Rehabilitation Medicine</topic><topic>Retrospective Studies</topic><topic>Surgical outcomes</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lodders, Johannes N.</creatorcontrib><creatorcontrib>van Baar, Gustaaf J. C.</creatorcontrib><creatorcontrib>Vergeer, Marije R.</creatorcontrib><creatorcontrib>Jansen, Femke</creatorcontrib><creatorcontrib>Schulten, Engelbert A. J. M.</creatorcontrib><creatorcontrib>Lissenberg-Witte, Birgit I.</creatorcontrib><creatorcontrib>Verdonck-de Leeuw, Irma M.</creatorcontrib><creatorcontrib>Forouzanfar, Tymour</creatorcontrib><creatorcontrib>Leusink, Frank K. J.</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Social Sciences Premium Collection</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Social Science Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Social Science Premium Collection</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Sociology Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Social Science Database</collection><collection>Sociology Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Supportive care in cancer</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lodders, Johannes N.</au><au>van Baar, Gustaaf J. C.</au><au>Vergeer, Marije R.</au><au>Jansen, Femke</au><au>Schulten, Engelbert A. J. M.</au><au>Lissenberg-Witte, Birgit I.</au><au>Verdonck-de Leeuw, Irma M.</au><au>Forouzanfar, Tymour</au><au>Leusink, Frank K. J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Implant-based dental rehabilitation in head and neck cancer patients after maxillofacial reconstruction with a free vascularized fibula flap: the effect on health-related quality of life</atitle><jtitle>Supportive care in cancer</jtitle><stitle>Support Care Cancer</stitle><addtitle>Support Care Cancer</addtitle><date>2022-06</date><risdate>2022</risdate><volume>30</volume><issue>6</issue><spage>5411</spage><epage>5420</epage><pages>5411-5420</pages><issn>0941-4355</issn><eissn>1433-7339</eissn><abstract>Purpose
To evaluate the effect of implant-based dental rehabilitation (IDR) on health-related quality of life (HRQoL) in head and neck cancer (HNC) patients after reconstruction with a free vascularized fibula flap (FFF).
Methods
Eligible patients were identified by retrospectively reviewing the medical records of patients treated in Amsterdam UMC-VUmc. HRQoL data were used from OncoQuest, a hospital-based system to collect patient-reported outcome measures in routine care. Data were used of the EORTC QLQ-C30 and QLQ-H&N 35 before FFF reconstruction (T
0
) and after completing IDR (T
1
). Data were statistically analysed with the chi-square test, independent samples
t
test and linear mixed models.
Results
Out of 96 patients with maxillofacial FFF reconstruction between January 2006 and October 2017, 57 patients (19 with and 38 without IDR) had HRQoL data at T
0
and T
1
. In the cross-sectional analysis, patients with IDR scored significantly better at T
0
and T
1
on several EORTC domains compared to the patients without IDR. Weight loss was significantly different in the within-subject analysis between T
0
and T
1
for patients with IDR (
p
= 0.011). However, there were no significant differences in the mean changes of all the EORTC QLQ-C30 and EORTC QLQ-H&N35 scores between the defined timepoints for patients with IDR compared to those without.
Conclusions
In this study, no differences were found in the course of HRQoL in HNC patients who had undergone IDR after maxillofacial FFF reconstruction, compared to those who had not. Patients should be preoperatively informed to have realistic expectations regarding the outcome of IDR.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>35298715</pmid><doi>10.1007/s00520-022-06944-4</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; SpringerLink Journals - AutoHoldings |
subjects | Analysis Cancer patients Cancer surgery Care and treatment Cross-Sectional Studies Dental implants Fibula Head & neck cancer Head and neck cancer Head and Neck Neoplasms - surgery Health aspects Humans Implant dentures Maxillofacial surgery Medical records Medicine Medicine & Public Health Nursing Nursing Research Oncology Original Original Article Pain Medicine Quality of Life Reconstructive surgery Rehabilitation Medicine Retrospective Studies Surgical outcomes |
title | Implant-based dental rehabilitation in head and neck cancer patients after maxillofacial reconstruction with a free vascularized fibula flap: the effect on health-related quality of life |
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