Characterization of P55, a multidrug efflux pump in Mycobacterium bovis and Mycobacterium tuberculosis

The Mycobacterium bovis P55 gene, located downstream from the gene that encodes the immunogenic lipoprotein P27, has been characterized. The gene was identical to the open reading frame of the Rv1410c gene in the genome of Mycobacterium tuberculosis H37Rv, annotated as a probable drug efflux protein...

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Veröffentlicht in:	Antimicrobial agents and chemotherapy 2001-03, Vol.45 (3), p.800-804
Hauptverfasser:	SILVA, Pedro E. A, BIGI, Fabiana, DE LA PAZ SANTANGELO, Maria, ROMANO, Maria Isabel, MARTIN, Carlos, CATALDI, Angel, AINSA, José A
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Motifs Anti-Bacterial Agents - pharmacology Bacterial Proteins - isolation & purification Bacterial Proteins - metabolism Bacteriology Biological and medical sciences Carrier Proteins - antagonists & inhibitors Carrier Proteins - isolation & purification Carrier Proteins - metabolism Databases, Factual Drug Resistance, Multiple Fundamental and applied biological sciences. Psychology Genetics Lipoproteins - physiology Mechanisms of Resistance Membrane Transport Proteins Microbial Sensitivity Tests Microbiology Mycobacterium bovis Mycobacterium bovis - drug effects Mycobacterium bovis - metabolism Mycobacterium tuberculosis Mycobacterium tuberculosis - drug effects Mycobacterium tuberculosis - metabolism P55 gene Streptomycin - pharmacology Subcellular Fractions Tetracycline Resistance - physiology Tetracyclines Verapamil - pharmacology
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