Synthesis and biological evaluation of novel artemisone-piperazine-tetronamide hybrids

For the first time, six novel artemisone-piperazine-tetronamide hybrids ( 12a-f ) were efficiently synthesised from dihydroartemisinin (DHA) and investigated for their in vitro cytotoxicity against some human cancer cells and benign cells. All the targets showed good cytotoxic activity in vitro . Hy...

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Veröffentlicht in:	RSC advances 2021-05, Vol.11 (3), p.18333-18341
Hauptverfasser:	Wei, Meng-Xue, Yu, Jia-Ying, Liu, Xin-Xin, Li, Xue-Qiang, Yang, Jin-Hui, Zhang, Meng-Wei, Yang, Pei-Wen, Zhang, Si-Si, He, Yu
Format:	Artikel
Sprache:	eng
Schlagworte:	Biotechnology Chemistry Liver cancer Toxicity
Online-Zugang:	Volltext
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