Glucose Metabolism, Neural Cell Senescence and Alzheimer's Disease

Alzheimer's disease (AD), an elderly neurodegenerative disorder with a high incidence and progressive memory decline, is one of the most expensive, lethal, and burdening diseases. To date, the pathogenesis of AD has not been fully illustrated. Emerging studies have revealed that cellular senesc...

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Veröffentlicht in:	International journal of molecular sciences 2022-04, Vol.23 (8), p.4351
Hauptverfasser:	Wang, Qianqian, Duan, Linyan, Li, Xingfan, Wang, Yifu, Guo, Wenna, Guan, Fangxia, Ma, Shanshan
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aging Alzheimer Disease - metabolism Alzheimer's disease Amyloid beta-Peptides - metabolism Astrocytes Brain Brain - metabolism Cell cycle Cellular Senescence Cognition & reasoning Dehydrogenases DNA damage Energy Enzymes Gene expression Glucose Glucose - metabolism Humans Insulin Kinases Lactic acid Metabolism Microglia Neurodegeneration Neurons Neurons - metabolism Oxidative stress Pathogenesis Pathology Phosphorylation Prevention Proteins Review Senescence Tau protein β-Amyloid
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