Histone Deacetylase Inhibitors Impair Glioblastoma Cell Motility and Proliferation

Despite being subjected to high-dose chemo and radiotherapy, glioblastoma (GBM) patients still encounter almost inevitable relapse, due to the capability of tumor cells to disseminate and invade normal brain tissues. Moreover, the presence of a cancer stem cell (CSC) subpopulation, already demonstra...

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Veröffentlicht in:	Cancers 2022-04, Vol.14 (8), p.1897
Hauptverfasser:	Rampazzo, Elena, Manfreda, Lorenzo, Bresolin, Silvia, Cani, Alice, Mariotto, Elena, Bortolozzi, Roberta, Della Puppa, Alessandro, Viola, Giampietro, Persano, Luca
Format:	Artikel
Sprache:	eng
Schlagworte:	Biotechnology Brain cancer Brain tumors Cancer therapies Cell culture Cell cycle Cell differentiation Cell migration Cell proliferation Cell viability Cofactors Colon cancer Colorectal cancer Flow cytometry Glioblastoma Growth factors Hepatocyte nuclear factor 1 Histone deacetylase Hypoxia Interferon Medical research Motility Patients Radiation therapy RhoA protein Software Stem cells Tumor cells Tumors Wnt protein β-Catenin
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