A study of the association between Vitamin D deficiency and Dry Eye Syndrome (DES) in the Indian population
Purpose: A study of the association between vitamin D deficiency and dry eye syndrome (DES) in the Indian population. Methods: This was a cross-sectional, hospital-based observational study. Sixty patients diagnosed with vitamin D deficiency (
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| Veröffentlicht in: | Indian journal of ophthalmology 2022-02, Vol.70 (2), p.500-504 |
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| creator | Jain, Nikita Sharma, Pankaj Chouhan, J |
| description | Purpose: A study of the association between vitamin D deficiency and dry eye syndrome (DES) in the Indian population. Methods: This was a cross-sectional, hospital-based observational study. Sixty patients diagnosed with vitamin D deficiency ( |
| doi_str_mv | 10.4103/ijo.IJO_1921_21 |
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Methods: This was a cross-sectional, hospital-based observational study. Sixty patients diagnosed with vitamin D deficiency (<20 ng/dl) who met the inclusion criteria were sent to the Eye OPD from the Endocrinology OPD (case) were compared to 60 subjects with normal vitamin D levels (≥20 ng/dl) who attended the Eye OPD (controls). The examination of the tear film was done using Whatman filter paper in Schirmer test I and Schirmer test I (with anesthesia). The tear film break-up time (TFBUT) was determined by slit-lamp examination using the fluorescein stain, and scoring using the ocular surface disease index (OSDI) was done. Results: A significant difference in the mean values of Schirmer I and Schirmer I test (with anesthesia) (P < 0.001) was seen between the case and control groups. A significant difference in the mean values of TFBUT (P < 0.001) and OSDI scores (P < 0.01) was also seen between the two groups. Conclusion: A positive association was found between vitamin D deficiency and dry eye on comparing the above parameters.</description><identifier>ISSN: 0301-4738</identifier><identifier>EISSN: 1998-3689</identifier><identifier>DOI: 10.4103/ijo.IJO_1921_21</identifier><identifier>PMID: 35086225</identifier><language>eng</language><publisher>India: Wolters Kluwer India Pvt. Ltd</publisher><subject>Alfacalcidol ; Anesthesia ; Calcifediol ; Care and treatment ; Cross-Sectional Studies ; Diagnosis ; Dosage and administration ; Dry eye syndromes ; Dry Eye Syndromes - diagnosis ; Dry Eye Syndromes - epidemiology ; Dry Eye Syndromes - etiology ; Endocrinology ; Eye ; Eye diseases ; Filter paper ; Fluorescein ; Humans ; Population studies ; Risk factors ; Special Focus, Ocular Surface, Original ; Tears ; Vitamin D ; Vitamin D deficiency ; Vitamin D Deficiency - complications ; Vitamin D Deficiency - diagnosis ; Vitamin D Deficiency - epidemiology ; Vitamin deficiency</subject><ispartof>Indian journal of ophthalmology, 2022-02, Vol.70 (2), p.500-504</ispartof><rights>COPYRIGHT 2022 Medknow Publications and Media Pvt. Ltd.</rights><rights>2022. This article is published under (http://creativecommons.org/licenses/by-nc-sa/3.0/) (the “License”). 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Methods: This was a cross-sectional, hospital-based observational study. Sixty patients diagnosed with vitamin D deficiency (<20 ng/dl) who met the inclusion criteria were sent to the Eye OPD from the Endocrinology OPD (case) were compared to 60 subjects with normal vitamin D levels (≥20 ng/dl) who attended the Eye OPD (controls). The examination of the tear film was done using Whatman filter paper in Schirmer test I and Schirmer test I (with anesthesia). The tear film break-up time (TFBUT) was determined by slit-lamp examination using the fluorescein stain, and scoring using the ocular surface disease index (OSDI) was done. Results: A significant difference in the mean values of Schirmer I and Schirmer I test (with anesthesia) (P < 0.001) was seen between the case and control groups. A significant difference in the mean values of TFBUT (P < 0.001) and OSDI scores (P < 0.01) was also seen between the two groups. Conclusion: A positive association was found between vitamin D deficiency and dry eye on comparing the above parameters.</description><subject>Alfacalcidol</subject><subject>Anesthesia</subject><subject>Calcifediol</subject><subject>Care and treatment</subject><subject>Cross-Sectional Studies</subject><subject>Diagnosis</subject><subject>Dosage and administration</subject><subject>Dry eye syndromes</subject><subject>Dry Eye Syndromes - diagnosis</subject><subject>Dry Eye Syndromes - epidemiology</subject><subject>Dry Eye Syndromes - etiology</subject><subject>Endocrinology</subject><subject>Eye</subject><subject>Eye diseases</subject><subject>Filter paper</subject><subject>Fluorescein</subject><subject>Humans</subject><subject>Population studies</subject><subject>Risk factors</subject><subject>Special Focus, Ocular Surface, Original</subject><subject>Tears</subject><subject>Vitamin D</subject><subject>Vitamin D deficiency</subject><subject>Vitamin D Deficiency - complications</subject><subject>Vitamin D Deficiency - diagnosis</subject><subject>Vitamin D Deficiency - epidemiology</subject><subject>Vitamin deficiency</subject><issn>0301-4738</issn><issn>1998-3689</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp9ksFv2yAUh61p05p2O-82Ie3SHZyCMRguk6Im2zJV6qRuuyKCn1MSG1JjL_J_X9K0XTtlEwck-N4HD35J8o7gcU4wPbMrP55_u1REZkRl5EUyIlKKlHIhXyYjTDFJ84KKo-Q4hBXGtCBSvE6OKMOCZxkbJesJCl1fDshXqLsGpEPwxurOeocW0G0BHPplO91Yh6aohMoaC84MSLsSTdsBzQZAV4MrW98AOp3Orj6iiO5Uc1da7dDGb_r6TvgmeVXpOsDb-_kk-fl59uP8a3px-WV-PrlIDc-KLuXYMFxBzgsGJRjGmCmFYHqRFWXFKgCaM5BFLmjGC5HTwhBYLDQjUElJuaEnyae9d9MvGigNuK7Vtdq0ttHtoLy26vmOs9dq6X8riTMqJY-C03tB6296CJ1qbDBQ19qB74PKeEaFEBmmEf3wF7ryfetie4qSnIlcFkL-j4qunHDMGP9DLXUNyrrKx9uZ3dFqwiUhNOccRyo9QC3BQWzFu_hDcfkZPz7Ax1FCY83BgrN9gWl9CC1Ujy9HsNqlTsXUqSepixXvnz74I_8Qswh83wNbX3fQhnXdb6FVkV07v_2XVzGM1UTd5VP5SsVQqYd80lsfvu3S</recordid><startdate>20220201</startdate><enddate>20220201</enddate><creator>Jain, Nikita</creator><creator>Sharma, Pankaj</creator><creator>Chouhan, J</creator><general>Wolters Kluwer India Pvt. 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Sharma, Pankaj ; Chouhan, J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c627t-60c50fe4675edec555cd885ab27df5fee345e974832678437c1ebba51ef9936c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Alfacalcidol</topic><topic>Anesthesia</topic><topic>Calcifediol</topic><topic>Care and treatment</topic><topic>Cross-Sectional Studies</topic><topic>Diagnosis</topic><topic>Dosage and administration</topic><topic>Dry eye syndromes</topic><topic>Dry Eye Syndromes - diagnosis</topic><topic>Dry Eye Syndromes - epidemiology</topic><topic>Dry Eye Syndromes - etiology</topic><topic>Endocrinology</topic><topic>Eye</topic><topic>Eye diseases</topic><topic>Filter paper</topic><topic>Fluorescein</topic><topic>Humans</topic><topic>Population studies</topic><topic>Risk factors</topic><topic>Special Focus, Ocular Surface, Original</topic><topic>Tears</topic><topic>Vitamin D</topic><topic>Vitamin D deficiency</topic><topic>Vitamin D Deficiency - complications</topic><topic>Vitamin D Deficiency - diagnosis</topic><topic>Vitamin D Deficiency - epidemiology</topic><topic>Vitamin deficiency</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jain, Nikita</creatorcontrib><creatorcontrib>Sharma, Pankaj</creatorcontrib><creatorcontrib>Chouhan, J</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Immunology Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Indian journal of ophthalmology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jain, Nikita</au><au>Sharma, Pankaj</au><au>Chouhan, J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A study of the association between Vitamin D deficiency and Dry Eye Syndrome (DES) in the Indian population</atitle><jtitle>Indian journal of ophthalmology</jtitle><addtitle>Indian J Ophthalmol</addtitle><date>2022-02-01</date><risdate>2022</risdate><volume>70</volume><issue>2</issue><spage>500</spage><epage>504</epage><pages>500-504</pages><issn>0301-4738</issn><eissn>1998-3689</eissn><abstract>Purpose: A study of the association between vitamin D deficiency and dry eye syndrome (DES) in the Indian population. Methods: This was a cross-sectional, hospital-based observational study. Sixty patients diagnosed with vitamin D deficiency (<20 ng/dl) who met the inclusion criteria were sent to the Eye OPD from the Endocrinology OPD (case) were compared to 60 subjects with normal vitamin D levels (≥20 ng/dl) who attended the Eye OPD (controls). The examination of the tear film was done using Whatman filter paper in Schirmer test I and Schirmer test I (with anesthesia). The tear film break-up time (TFBUT) was determined by slit-lamp examination using the fluorescein stain, and scoring using the ocular surface disease index (OSDI) was done. Results: A significant difference in the mean values of Schirmer I and Schirmer I test (with anesthesia) (P < 0.001) was seen between the case and control groups. A significant difference in the mean values of TFBUT (P < 0.001) and OSDI scores (P < 0.01) was also seen between the two groups. Conclusion: A positive association was found between vitamin D deficiency and dry eye on comparing the above parameters.</abstract><cop>India</cop><pub>Wolters Kluwer India Pvt. Ltd</pub><pmid>35086225</pmid><doi>10.4103/ijo.IJO_1921_21</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| issn | 0301-4738 1998-3689 |
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| subjects | Alfacalcidol Anesthesia Calcifediol Care and treatment Cross-Sectional Studies Diagnosis Dosage and administration Dry eye syndromes Dry Eye Syndromes - diagnosis Dry Eye Syndromes - epidemiology Dry Eye Syndromes - etiology Endocrinology Eye Eye diseases Filter paper Fluorescein Humans Population studies Risk factors Special Focus, Ocular Surface, Original Tears Vitamin D Vitamin D deficiency Vitamin D Deficiency - complications Vitamin D Deficiency - diagnosis Vitamin D Deficiency - epidemiology Vitamin deficiency |
| title | A study of the association between Vitamin D deficiency and Dry Eye Syndrome (DES) in the Indian population |
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