Effects of Treadmill Exercise on Mitochondrial DNA Damage and Cardiomyocyte Telomerase Activity in Aging Model Rats Based on Classical Apoptosis Signaling Pathway

In order to explore the effect of treadmill exercise on mitochondrial DNA damage and myocardial telomerase activity in aging model rats based on the classical apoptosis signaling pathway, a total of 36 clean-grade male SD rats are selected. After modeling, the rats are randomly divided into groups,...

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Veröffentlicht in:	BioMed research international 2022-04, Vol.2022, p.3529499-8
Hauptverfasser:	Liang, Chao, Zhou, Xiaoli, Li, Meiling, Song, Zhengpeng, Lan, Jinyan
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Aging - genetics Aging - metabolism AKT2 protein Animals Antibodies Apoptosis BAX protein Bcl-2 protein bcl-2-Associated X Protein - genetics bcl-2-Associated X Protein - metabolism Cardiomyocytes Damage Data analysis DNA damage DNA, Mitochondrial - genetics DNA, Mitochondrial - metabolism Exercise Exercise Therapy - methods Fitness equipment Health aspects Heart Heart cells Male Mitochondrial DNA Myocytes, Cardiac - metabolism Physiological aspects Physiological research Proteins Proto-Oncogene Proteins c-bcl-2 - genetics Proto-Oncogene Proteins c-bcl-2 - metabolism Rats Rats, Sprague-Dawley Signal Transduction Signaling Telomerase Telomerase - genetics Telomerase - metabolism Treadmill exercise tests Treadmills Western blotting
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