Noninvasive biomarkers identify eosinophilic esophagitis: A prospective longitudinal study in children

ABSTRACT Background Esophageal histology is critical for diagnosis and surveillance of disease activity in eosinophilic esophagitis (EoE). A validated noninvasive biomarker has not been identified. We aimed to determine the utility of blood and urine eosinophil‐associated proteins to diagnose EoE an...

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Veröffentlicht in:	Allergy (Copenhagen) 2021-12, Vol.76 (12), p.3755-3765
Hauptverfasser:	Wechsler, Joshua B., Ackerman, Steven J., Chehade, Mirna, Amsden, Katie, Riffle, Mary E., Wang, Ming‐Yu, Du, Jian, Kleinjan, Matt L., Alumkal, Preeth, Gray, Elizabeth, Kim, Kwang‐Youn A., Wershil, Barry K., Kagalwalla, Amir F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergies Atopy Autoimmune diseases biomarker Biomarkers Biopsy blood Blood diseases Child Children Diagnosis Endoscopy eosinophil Eosinophil cationic protein Eosinophil-Derived Neurotoxin - metabolism Eosinophilia eosinophilic esophagitis Eosinophilic Esophagitis - metabolism Eosinophils - metabolism Eotaxin Esophageal diseases Esophagitis Esophagus Gastrointestinal diseases Humans Leukocytes Leukocytes (eosinophilic) Longitudinal Studies Matrix metalloproteinase Metalloproteinase noninvasive Osteopontin Patients Prospective Studies Urine
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