Anti-HIV Drugs Cause Mitochondrial Dysfunction in Monocyte-Derived Macrophages

Combination antiretroviral therapy (cART) dramatically changed the face of the HIV/AIDS pandemic, making it one of the most prominent medical breakthroughs of the past 3 decades. However, as the life span of persons living with HIV (PLWH) continues to approach that of the general population, the sam...

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Veröffentlicht in:	Antimicrobial agents and chemotherapy 2022-04, Vol.66 (4), p.e0194121-e0194121
Hauptverfasser:	Wallace, Jennillee, Gonzalez, Hemil, Rajan, Reshma, Narasipura, Srinivas D, Virdi, Amber K, Olali, Arnold Z, Naqib, Ankur, Arbieva, Zarema, Maienschein-Cline, Mark, Al-Harthi, Lena
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-HIV Agents - therapeutic use Antiviral Agents Efavirenz, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination - metabolism Efavirenz, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination - pharmacology Efavirenz, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination - therapeutic use HIV Infections HIV-1 Humans Immunology Macrophages Mitochondria Quality of Life
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