Multiplexed imaging and automated signal quantification in formalin-fixed paraffin-embedded tissues by ChipCytometry

Deciphering the spatial composition of cells in tissues is essential for detailed understanding of biological processes in health and disease. Recent technological advances enabled the assessment of the enormous complexity of tissue-derived parameters by highly multiplexed tissue imaging (HMTI), but...

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Veröffentlicht in:	Cell reports methods 2021-11, Vol.1 (7), p.100104-100104, Article 100104
Hauptverfasser:	Jarosch, Sebastian, Köhlen, Jan, Sarker, Rim S.J., Steiger, Katja, Janssen, Klaus-Peter, Christians, Arne, Hennig, Christian, Holler, Ernst, D'Ippolito, Elvira, Busch, Dirk H.
Format:	Artikel
Sprache:	eng
Schlagworte:	automated quantification of signal intensities cell-type segmentation formalin-fixed paraffin-embedded samples highly multiplexed tissue imaging spatial spillover correction
Online-Zugang:	Volltext
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