SARS-COV-2 - the pandemic of the XXI century, clinical manifestations - neurological implications

In December 2019, in Wuhan, China, the first cases of infection with SARS-CoV 2 responsible for COVID-19 disease were identified. SARS-CoV 2 was declared a pandemic on March 11, 2020, and since then has attracted the medical world's attention. The threat to humans' health that this emergin...

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Veröffentlicht in:Journal of medicine and life 2022-03, Vol.15 (3), p.319-327
Hauptverfasser: Saceleanu, Vicentiu, Moreanu, Mihai-Stelian, Covache-Busuioc, Razvan-Adrian, Mohan, Aurel George, Ciurea, Alexandru-Vlad
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container_end_page 327
container_issue 3
container_start_page 319
container_title Journal of medicine and life
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creator Saceleanu, Vicentiu
Moreanu, Mihai-Stelian
Covache-Busuioc, Razvan-Adrian
Mohan, Aurel George
Ciurea, Alexandru-Vlad
description In December 2019, in Wuhan, China, the first cases of infection with SARS-CoV 2 responsible for COVID-19 disease were identified. SARS-CoV 2 was declared a pandemic on March 11, 2020, and since then has attracted the medical world's attention. The threat to humans' health that this emerging pandemic could leave raises awareness on the importance of understanding the mechanisms that underlie the developing conditions. The epidemiology, clinical picture, and pathogenesis of COVID-19 show that this virus presents new strategies to overcome the past defensive medicine. While all the current data has focused on the pulmonary and cardiovascular manifestations, little has been written about the neurological implications of the disease. This review updates new clinical aspects that SARS-CoV 2 expresses in humans by focusing primarily on neurological manifestations. The damage to the nervous system became more apparent - anosmia, ageusia, polyneuritis, meningitis, meningoencephalitis, stroke, acute necrotizing encephalopathy. Oxygen therapy is vital for those in critical health situations. Finally, prevention is the most important element in breaking the epidemiological chain.
doi_str_mv 10.25122/jml-2020-0151
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E-mail: moreanumihai@yahoo.com ; Department of Neurosurgery, County Emergency Hospital, Sibiu, Romania ; Department of Neurosurgery, County Emergency Hospital, Oradea, Romania ; Department of Neurosurgery, Faculty of Medicine and Pharmacy, University of Oradea, Oradea, Romania ; Department of Neurosurgery, Faculty of Medicine, Lucian Blaga University, Sibiu, Romania ; Department of Neurosurgery, Sanador Clinical Hospital, Bucharest, Romania</creatorcontrib><description>In December 2019, in Wuhan, China, the first cases of infection with SARS-CoV 2 responsible for COVID-19 disease were identified. SARS-CoV 2 was declared a pandemic on March 11, 2020, and since then has attracted the medical world's attention. The threat to humans' health that this emerging pandemic could leave raises awareness on the importance of understanding the mechanisms that underlie the developing conditions. The epidemiology, clinical picture, and pathogenesis of COVID-19 show that this virus presents new strategies to overcome the past defensive medicine. While all the current data has focused on the pulmonary and cardiovascular manifestations, little has been written about the neurological implications of the disease. This review updates new clinical aspects that SARS-CoV 2 expresses in humans by focusing primarily on neurological manifestations. The damage to the nervous system became more apparent - anosmia, ageusia, polyneuritis, meningitis, meningoencephalitis, stroke, acute necrotizing encephalopathy. Oxygen therapy is vital for those in critical health situations. 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source MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; PubMed Central Open Access
subjects Coronaviruses
COVID-19
Epidemics
Fatalities
Humans
Nervous System Diseases - epidemiology
Nervous System Diseases - etiology
Pandemics
Review
SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2
Stroke - complications
title SARS-COV-2 - the pandemic of the XXI century, clinical manifestations - neurological implications
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