Strategies to Diagnose Nonalcoholic Steatohepatitis: A Novel Approach to Take Advantage of Pharmacokinetic Alterations

Nonalcoholic steatohepatitis (NASH) is the progressive form of nonalcoholic fatty liver disease (NAFLD) and is diagnosed by a liver biopsy. Because of the invasiveness of a biopsy, the majority of patients with NASH are undiagnosed. Additionally, the prevalence of NAFLD and NASH creates the need for...

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Veröffentlicht in:	Drug metabolism and disposition 2022-04, Vol.50 (4), p.492-499
Hauptverfasser:	Marie, Solène, Tripp, David K K, Cherrington, Nathan J
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers - metabolism Biopsy Drug-Related Side Effects and Adverse Reactions Humans Liver - metabolism Non-alcoholic Fatty Liver Disease - diagnosis Non-alcoholic Fatty Liver Disease - pathology Special Section on Bile Acids, Drug Metabolism, and Toxicity
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