Efficacy and safety of trifluridine/tipiracil in older and younger patients with metastatic gastric or gastroesophageal junction cancer: subgroup analysis of a randomized phase 3 study (TAGS)

Background Trifluridine and tipiracil (FTD/TPI) demonstrated survival benefit vs placebo and manageable safety in previously treated patients with metastatic gastric/gastroesophageal junction cancer (mGC/GEJC) in the randomized, placebo-controlled, phase 3 TAGS study. This subgroup analysis of TAGS...

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Veröffentlicht in:	Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2022-05, Vol.25 (3), p.586-597
Hauptverfasser:	Shitara, Kohei, Doi, Toshihiko, Hosaka, Hisashi, Thuss-Patience, Peter, Santoro, Armando, Longo, Federico, Ozyilkan, Ozgur, Cicin, Irfan, Park, David, Zaanan, Aziz, Pericay, Carles, Özgüroğlu, Mustafa, Alsina, Maria, Makris, Lukas, Benhadji, Karim A., Ilson, David H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdominal Surgery Age Aged Antineoplastic Combined Chemotherapy Protocols - adverse effects Antiviral drugs Cancer Research Colorectal Neoplasms - pathology Drug Combinations Esophageal Neoplasms - drug therapy Esophagogastric Junction - pathology Frontotemporal dementia Frontotemporal Dementia - chemically induced Frontotemporal Dementia - drug therapy Gastric cancer Gastroenterology Humans Medicine Medicine & Public Health Metastases Metastasis Neutropenia Oncology Original Original Article Patients Placebos Pyrrolidines Safety Stomach Neoplasms - pathology Surgical Oncology Survival Thymine Trifluridine - adverse effects
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