Mechanotherapy Reprograms Aged Muscle Stromal Cells to Remodel the Extracellular Matrix during Recovery from Disuse

Aging is accompanied by reduced remodeling of skeletal muscle extracellular matrix (ECM), which is exacerbated during recovery following periods of disuse atrophy. Mechanotherapy has been shown to promote ECM remodeling through immunomodulation in adult muscle recovery, but not during the aged recov...

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Veröffentlicht in:	Function 2022, Vol.3 (3), p.zqac015-zqac015
Hauptverfasser:	Hettinger, Zachary R, Wen, Yuan, Peck, Bailey D, Hamagata, Kyoko, Confides, Amy L, Van Pelt, Douglas W, Harrison, Douglas A, Miller, Benjamin F, Butterfield, Timothy A, Dupont-Versteegden, Esther E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Collagen Endothelial Cells Extracellular Matrix Gene expression Genes Macrophages Muscle, Skeletal - metabolism Muscles Muscular Disorders, Atrophic - metabolism Rats RNA RNA sequencing
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