The tumor suppressor adenomatous polyposis coli regulates T lymphocyte migration

Adenomatous polyposis coli (APC) is a tumor suppressor whose mutations underlie familial adenomatous polyposis (FAP) and colorectal cancer. Although its role in intestinal epithelial cells is well characterized, APC importance in T cell biology is ill defined. APC regulates cytoskeleton organization...

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Veröffentlicht in:	Science advances 2022-04, Vol.8 (15), p.eabl5942-eabl5942
Hauptverfasser:	Mastrogiovanni, Marta, Vargas, Pablo, Rose, Thierry, Cuche, Céline, Esposito, Elric, Juzans, Marie, Laude, Hélène, Schneider, Amandine, Bernard, Mathilde, Goyard, Sophie, Renaudat, Charlotte, Ungeheuer, Marie-Noëlle, Delon, Jérôme, Alcover, Andrés, Di Bartolo, Vincenzo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenomatous Polyposis Coli Adenomatous Polyposis Coli - genetics Adenomatous Polyposis Coli Protein Adenomatous Polyposis Coli Protein - genetics Biomedicine and Life Sciences Cell Biology Cell Movement Humans Immunology Life Sciences Mutation Phenotype SciAdv r-articles
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