Semiconducting Polymers for Neural Applications

Electronically interfacing with the nervous system for the purposes of health diagnostics and therapy, sports performance monitoring, or device control has been a subject of intense academic and industrial research for decades. This trend has only increased in recent years, with numerous high-profil...

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Veröffentlicht in:Chemical reviews 2022-02, Vol.122 (4), p.4356-4396
Hauptverfasser: Dimov, Ivan B, Moser, Maximilian, Malliaras, George G, McCulloch, Iain
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creator Dimov, Ivan B
Moser, Maximilian
Malliaras, George G
McCulloch, Iain
description Electronically interfacing with the nervous system for the purposes of health diagnostics and therapy, sports performance monitoring, or device control has been a subject of intense academic and industrial research for decades. This trend has only increased in recent years, with numerous high-profile research initiatives and commercial endeavors. An important research theme has emerged as a result, which is the incorporation of semiconducting polymers in various devices that communicate with the nervous systemfrom wearable brain-monitoring caps to penetrating implantable microelectrodes. This has been driven by the potential of this broad class of materials to improve the electrical and mechanical properties of the tissue–device interface, along with possibilities for increased biocompatibility. In this review we first begin with a tutorial on neural interfacing, by reviewing the basics of nervous system function, device physics, and neuroelectrophysiological techniques and their demands, and finally we give a brief perspective on how material improvements can address current deficiencies in this system. The second part is a detailed review of past work on semiconducting polymers, covering electrical properties, structure, synthesis, and processing.
doi_str_mv 10.1021/acs.chemrev.1c00685
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subjects Biocompatibility
Brain
Chemical synthesis
Electrical properties
Industrial research
Mechanical properties
Microelectrodes
Nervous System
Polymers
Polymers - chemistry
Prostheses and Implants
R&D
Research & development
Review
title Semiconducting Polymers for Neural Applications
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