LINC00114 stimulates growth and glycolysis of esophageal cancer cells by recruiting EZH2 to enhance H3K27me3 of DLC1

LINC00114 could promote the development of colorectal cancer, but its mechanism has been rarely discussed in esophageal cancer (EC). Herein, we explored the molecular mechanism of LINC00114 via mediating enhancer of zeste homolog 2/deleted in liver cancer 1 (EZH2/DLC1) axis in EC. LINC00114, EZH2 an...

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Veröffentlicht in:	Clinical epigenetics 2022-12, Vol.14 (1), p.51-51, Article 51
Hauptverfasser:	Qin, Jianzhang, Li, Yishuai, Li, Zhe, Qin, Xuebo, Zhou, Xuetao, Zhang, Hao, Li, Shujun
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Apoptosis Cancer therapies Cell Line, Tumor Cell migration Cell proliferation Colorectal cancer Colorectal carcinoma Development and progression DNA Methylation Enhancer of Zeste Homolog 2 Protein - genetics Enhancer of Zeste Homolog 2 Protein - metabolism Esophageal cancer Esophageal Neoplasms - metabolism Ethics Fluorides Gene expression Gene Expression Regulation, Neoplastic Glucose metabolism Glycolysis Growth GTPase-Activating Proteins - genetics Histones - metabolism Humans Liver Liver cancer Medical prognosis Metabolism Metabolites Methylation Proteins Transfection Tumor Suppressor Proteins - genetics Tumor Suppressor Proteins - metabolism Tumors
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