Tunable Properties via Composition Modulations of Poly(vinyl alcohol)/Xanthan Gum/Oxalic Acid Hydrogels
The design of hydrogel networks with tuned properties is essential for new innovative biomedical materials. Herein, poly(vinyl alcohol) and xanthan gum were used to develop hydrogels by the freeze/thaw cycles method in the presence of oxalic acid as a crosslinker. The structure and morphology of the...
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| Veröffentlicht in: | Materials 2022-04, Vol.15 (7), p.2657 |
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| creator | Enache, Alin Alexandru Serbezeanu, Diana Vlad-Bubulac, Tăchiță Ipate, Alina-Mirela Suflet, Dana Mihaela Drobotă, Mioara Barbălată-Mândru, Mihaela Udrea, Radu Mihail Rîmbu, Cristina Mihaela |
| description | The design of hydrogel networks with tuned properties is essential for new innovative biomedical materials. Herein, poly(vinyl alcohol) and xanthan gum were used to develop hydrogels by the freeze/thaw cycles method in the presence of oxalic acid as a crosslinker. The structure and morphology of the obtained hydrogels were investigated by means of scanning electron microscopy (SEM), Fourier transform infrared (FTIR) spectroscopy, and swelling behavior. The SEM analysis revealed that the surface morphology was mostly affected by the blending ratio between the two components, namely, poly(vinyl alcohol) and xanthan gum. From the swelling study, it was observed that the presence of oxalic acid influenced the hydrophilicity of blends. The hydrogels based on poly(vinyl alcohol) without xanthan gum led to structures with a smaller pore diameter, a lower swelling degree in pH 7.4 buffer solution, and a higher elastic modulus. The antimicrobial activity of the prepared hydrogels was tested and the results showed that the hydrogels conferred antibacterial activity against Gram positive bacteria (
) and Gram negative bacteria (
). |
| doi_str_mv | 10.3390/ma15072657 |
| format | Article |
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) and Gram negative bacteria (
).</description><subject>Acids</subject><subject>Alcohol</subject><subject>Antimicrobial agents</subject><subject>Biomedical materials</subject><subject>Buffer solutions</subject><subject>Coliforms</subject><subject>E coli</subject><subject>Ethanol</subject><subject>Fourier transforms</subject><subject>Hydrogels</subject><subject>Infrared analysis</subject><subject>Mechanical properties</subject><subject>Methods</subject><subject>Modulus of elasticity</subject><subject>Morphology</subject><subject>Oxalic acid</subject><subject>Polymer blends</subject><subject>Polymers</subject><subject>Polyvinyl alcohol</subject><subject>Scanning electron microscopy</subject><subject>Swelling</subject><subject>Viscosity</subject><subject>Xanthan</subject><issn>1996-1944</issn><issn>1996-1944</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNpdkclKBDEQhoMoKurFB5CAFxXGydad5CLI4AaKHubgLaTT6ZlIOhmT7sF5e9t9qUsVVR8_VfUDsI_RKaUSjVuNC8RJWfA1sI2lLEdYMrb-q94Cezk_oSEoxYLITbBFC4a4FHIbzKZ90JW38CHFhU2dsxkunYaT2C5idp2LAd7Fuvf6rcwwNvAh-tXR0oWVh9qbOI_-ePyoQzfXAV717fj-RXtn4LlxNbxe1SnOrM-7YKPRPtu9z7wDppcX08n16Pb-6mZyfjsyDJXdSJqi4rXlFZEEGVRYzDXhlkmDMG0Yr0uBCCkbLBjlpBGCWVERRKisLR16O-DsQ3bRV62tjQ1d0l4tkmt1Wqmonfo7CW6uZnGp5PAezopB4OhTIMXn3uZOtS4b670ONvZZkZLJQvCiFAN6-A99in0Kw3XvFCKIi3KgTj4ok2LOyTbfy2Ck3hxUPw4O8MHv9b_RL7_oK8s4lks</recordid><startdate>20220404</startdate><enddate>20220404</enddate><creator>Enache, Alin Alexandru</creator><creator>Serbezeanu, Diana</creator><creator>Vlad-Bubulac, Tăchiță</creator><creator>Ipate, Alina-Mirela</creator><creator>Suflet, Dana Mihaela</creator><creator>Drobotă, Mioara</creator><creator>Barbălată-Mândru, Mihaela</creator><creator>Udrea, Radu Mihail</creator><creator>Rîmbu, Cristina Mihaela</creator><general>MDPI AG</general><general>MDPI</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SR</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>HCIFZ</scope><scope>JG9</scope><scope>KB.</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-8544-5671</orcidid><orcidid>https://orcid.org/0000-0001-7206-1134</orcidid><orcidid>https://orcid.org/0000-0003-0982-0040</orcidid><orcidid>https://orcid.org/0000-0002-9017-9926</orcidid><orcidid>https://orcid.org/0000-0002-3528-140X</orcidid><orcidid>https://orcid.org/0000-0002-6250-3477</orcidid></search><sort><creationdate>20220404</creationdate><title>Tunable Properties via Composition Modulations of Poly(vinyl alcohol)/Xanthan Gum/Oxalic Acid Hydrogels</title><author>Enache, Alin Alexandru ; 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Herein, poly(vinyl alcohol) and xanthan gum were used to develop hydrogels by the freeze/thaw cycles method in the presence of oxalic acid as a crosslinker. The structure and morphology of the obtained hydrogels were investigated by means of scanning electron microscopy (SEM), Fourier transform infrared (FTIR) spectroscopy, and swelling behavior. The SEM analysis revealed that the surface morphology was mostly affected by the blending ratio between the two components, namely, poly(vinyl alcohol) and xanthan gum. From the swelling study, it was observed that the presence of oxalic acid influenced the hydrophilicity of blends. The hydrogels based on poly(vinyl alcohol) without xanthan gum led to structures with a smaller pore diameter, a lower swelling degree in pH 7.4 buffer solution, and a higher elastic modulus. The antimicrobial activity of the prepared hydrogels was tested and the results showed that the hydrogels conferred antibacterial activity against Gram positive bacteria (
) and Gram negative bacteria (
).</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>35407989</pmid><doi>10.3390/ma15072657</doi><orcidid>https://orcid.org/0000-0001-8544-5671</orcidid><orcidid>https://orcid.org/0000-0001-7206-1134</orcidid><orcidid>https://orcid.org/0000-0003-0982-0040</orcidid><orcidid>https://orcid.org/0000-0002-9017-9926</orcidid><orcidid>https://orcid.org/0000-0002-3528-140X</orcidid><orcidid>https://orcid.org/0000-0002-6250-3477</orcidid><oa>free_for_read</oa></addata></record> |
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| ispartof | Materials, 2022-04, Vol.15 (7), p.2657 |
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| language | eng |
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| source | MDPI - Multidisciplinary Digital Publishing Institute; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Free Full-Text Journals in Chemistry; PubMed Central Open Access |
| subjects | Acids Alcohol Antimicrobial agents Biomedical materials Buffer solutions Coliforms E coli Ethanol Fourier transforms Hydrogels Infrared analysis Mechanical properties Methods Modulus of elasticity Morphology Oxalic acid Polymer blends Polymers Polyvinyl alcohol Scanning electron microscopy Swelling Viscosity Xanthan |
| title | Tunable Properties via Composition Modulations of Poly(vinyl alcohol)/Xanthan Gum/Oxalic Acid Hydrogels |
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