Serum IL6 as a Prognostic Biomarker and IL6R as a Therapeutic Target in Biliary Tract Cancers

Purpose: Biliary tract cancer (BTC) is a heterogeneous group of rare gastrointestinal malignancies with dismal prognosis often associated with inflammation. We assessed the prognostic value of IL6 and YKL-40 compared with CA19-9 before and during palliative chemotherapy. We also investigated in mice...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Clinical cancer research 2020-11, Vol.26 (21), p.5655-5667
Hauptverfasser:	Hogdall, Dan, O'Rourke, Colm J., Dehlendorff, Christian, Larsen, Ole F., Jensen, Lars H., Johansen, Astrid Z., Dang, Hien, Factor, Valentina M., Grunnet, Mie, Mau-Sorensen, Morten, Oliveira, Douglas V. N. P., Linnemann, Dorte, Boisen, Mogens K., Wang, Xin W., Johansen, Julia S., Andersen, Jesper B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Animals Antigens, Tumor-Associated, Carbohydrate - blood Antigens, Tumor-Associated, Carbohydrate - genetics Antineoplastic Combined Chemotherapy Protocols - administration & dosage Antineoplastic Combined Chemotherapy Protocols - adverse effects Biliary Tract Neoplasms - blood Biliary Tract Neoplasms - drug therapy Biliary Tract Neoplasms - genetics Biliary Tract Neoplasms - pathology Biomarkers, Tumor - blood Cell Proliferation - drug effects Chitinase-3-Like Protein 1 - blood Chitinase-3-Like Protein 1 - genetics Deoxycytidine - administration & dosage Deoxycytidine - adverse effects Deoxycytidine - analogs & derivatives Disease-Free Survival Female Humans Interleukin-6 - blood Interleukin-6 - genetics Life Sciences & Biomedicine Male Mice Middle Aged Oncology Palliative Care Prognosis Progression-Free Survival Receptors, Interleukin-6 - antagonists & inhibitors Receptors, Interleukin-6 - blood Receptors, Interleukin-6 - genetics Science & Technology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!