The impact of euploid blastocyst morphology and maternal age on pregnancy and neonatal outcomes in natural cycle frozen embryo transfers

The impact of euploid blastocyst morphology and maternal age on pregnancy and neonatal outcomes in natural cycle frozen embryo transfers

Purpose To evaluate whether morphology impacts the pregnancy and neonatal outcomes of euploid blastocysts, and whether maternal age still affects outcomes when top-graded, euploid blastocysts are used. Methods This retrospective cohort study included all natural-cycle frozen embryo transfers (NC-FET...

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Veröffentlicht in:Journal of assisted reproduction and genetics 2022-03, Vol.39 (3), p.647-654
Hauptverfasser: Zhang, Wendy Y., Johal, Jasmyn K., Gardner, Rebecca M., Bavan, Brindha, Milki, Amin A.
Format: Artikel
Sprache:eng
Schlagworte:
Age
Age groups
Assisted Reproduction Technologies
Birth Weight
Blastocyst
Blastocysts
Embryo Implantation
Embryo Transfer
Embryos
Female
Gestational age
Gynecology
Human Genetics
Humans
Infant, Newborn
Maternal Age
Medicine
Medicine & Public Health
Morphology
Neonates
Pregnancy
Pregnancy Rate
Regression analysis
Reproductive Medicine
Retrospective Studies
Statistical analysis
Trophectoderm
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Zusammenfassung:Purpose To evaluate whether morphology impacts the pregnancy and neonatal outcomes of euploid blastocysts, and whether maternal age still affects outcomes when top-graded, euploid blastocysts are used. Methods This retrospective cohort study included all natural-cycle frozen embryo transfers (NC-FET) using an autologous, euploid blastocyst from June 2016 to June 2020 ( n  = 610). There were five groups based on embryo grade: AA, AB, BA, BB, and “any C”. For analysis of only AA-graded embryos, there were three maternal age groups: 
ISSN:1058-0468
1573-7330
DOI:10.1007/s10815-022-02423-1