Comparative Risk of Alzheimer Disease and Related Dementia Among Medicare Beneficiaries With Rheumatoid Arthritis Treated With Targeted Disease-Modifying Antirheumatic Agents

Cytokine signaling, including tumor necrosis factor (TNF) and interleukin (IL)-6, through the Janus-kinase (JAK)-signal transducer and activator of transcription pathway, was hypothesized to attenuate the risk of Alzheimer disease and related dementia (ADRD) in the Drug Repurposing for Effective Alz...

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Veröffentlicht in:	JAMA network open 2022-04, Vol.5 (4), p.e226567-e226567
Hauptverfasser:	Desai, Rishi J, Varma, Vijay R, Gerhard, Tobias, Segal, Jodi, Mahesri, Mufaddal, Chin, Kristyn, Horton, Daniel B, Kim, Seoyoung C, Schneeweiss, Sebastian, Thambisetty, Madhav
Format:	Artikel
Sprache:	eng
Schlagworte:	Abatacept - therapeutic use Aged Alzheimer Disease - chemically induced Alzheimer Disease - drug therapy Alzheimer Disease - epidemiology Antirheumatic Agents - adverse effects Arthritis, Rheumatoid - chemically induced Arthritis, Rheumatoid - drug therapy Arthritis, Rheumatoid - epidemiology Cardiovascular disease Cardiovascular Diseases - drug therapy Cohort Studies Dementia Female Humans Medicare Monoclonal antibodies Neurology Online Only Original Investigation Rheumatoid arthritis TNF inhibitors Tumor Necrosis Factor Inhibitors Tumor necrosis factor-TNF United States - epidemiology Vitamin E
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