Testosterone, estradiol, DHEA and cortisol in relation to anxiety and depression scores in adolescents

•In 2016, we examined 545 boys and girls (ages 11–17y) in rural Ecuador.•Elevated testosterone, cortisol and estradiol were associated with altered mood.•Estradiol had the strongest associations with depression and anxiety scores.•Cortisol and Testosterone were effect modifiers to hormone-mood assoc...

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