Phosphodiesterase type 4 anchoring regulates cAMP signaling to Popeye domain-containing proteins

Cyclic AMP is a ubiquitous second messenger used to transduce intracellular signals from a variety of Gs-coupled receptors. Compartmentalisation of protein intermediates within the cAMP signaling pathway underpins receptor-specific responses. The cAMP effector proteins protein-kinase A and EPAC are...

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Veröffentlicht in:Journal of molecular and cellular cardiology 2022-04, Vol.165, p.86-102
Hauptverfasser: Tibbo, Amy J., Mika, Delphine, Dobi, Sara, Ling, Jiayue, McFall, Aisling, Tejeda, Gonzalo S., Blair, Connor, MacLeod, Ruth, MacQuaide, Niall, Gök, Caglar, Fuller, William, Smith, Brian O., Smith, Godfrey L., Vandecasteele, Grégoire, Brand, Thomas, Baillie, George S.
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Sprache:eng
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