The Essentials of Multiomics

Within the last decade, the science of molecular testing has evolved from single gene and single protein analysis to broad molecular profiling as a standard of care, quickly transitioning from research to practice. Terms such as genomics, transcriptomics, proteomics, circulating omics, and artificia...

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Veröffentlicht in:The oncologist (Dayton, Ohio) Ohio), 2022-04, Vol.27 (4), p.272-284
Hauptverfasser: Marshall, John L, Peshkin, Beth N, Yoshino, Takayuki, Vowinckel, Jakob, Danielsen, Håvard E, Melino, Gerry, Tsamardinos, Ioannis, Haudenschild, Christian, Kerr, David J, Sampaio, Carlos, Rha, Sun Young, FitzGerald, Kevin T, Holland, Eric C, Gallagher, David, Garcia-Foncillas, Jesus, Juhl, Hartmut
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container_end_page 284
container_issue 4
container_start_page 272
container_title The oncologist (Dayton, Ohio)
container_volume 27
creator Marshall, John L
Peshkin, Beth N
Yoshino, Takayuki
Vowinckel, Jakob
Danielsen, Håvard E
Melino, Gerry
Tsamardinos, Ioannis
Haudenschild, Christian
Kerr, David J
Sampaio, Carlos
Rha, Sun Young
FitzGerald, Kevin T
Holland, Eric C
Gallagher, David
Garcia-Foncillas, Jesus
Juhl, Hartmut
description Within the last decade, the science of molecular testing has evolved from single gene and single protein analysis to broad molecular profiling as a standard of care, quickly transitioning from research to practice. Terms such as genomics, transcriptomics, proteomics, circulating omics, and artificial intelligence are now commonplace, and this rapid evolution has left us with a significant knowledge gap within the medical community. In this paper, we attempt to bridge that gap and prepare the physician in oncology for multiomics, a group of technologies that have gone from looming on the horizon to become a clinical reality. The era of multiomics is here, and we must prepare ourselves for this exciting new age of cancer medicine.
doi_str_mv 10.1093/oncolo/oyab048
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subjects Antimitotic agents
Antineoplastic agents
Artificial Intelligence
Cancer Diagnostics and Molecular Pathology
Genes
Genomics
Humans
Machine learning
Medical Oncology
Neoplasms - genetics
Neoplasms - therapy
Proteomics
title The Essentials of Multiomics
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