ANGPTL4 regulate glutamine metabolism and fatty acid oxidation in nonsmall cell lung cancer cells

Angiopoietin‐like protein (ANGPTL) 4 is a key factor in the regulation of lipid and glucose metabolism in metabolic diseases. ANGPTL4 is highly expressed in various cancers, but the regulation of energy metabolism in tumours remains to be determined. This study explored the role of ANGPTL4 in aerobi...

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Veröffentlicht in:	Journal of cellular and molecular medicine 2022-04, Vol.26 (7), p.1876-1885
Hauptverfasser:	Xiao, Song, Nai‐dong, Wang, Jin‐Xiang, Yan, Long, Tian, Xiu‐Rong, Lu, Hong, Gao, Jie‐Cheng, Yan, Fei, Zhang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine triphosphate aerobic glycolysis Angiogenesis Angiopoietin ANGPTL4 Animals Carcinoma, Non-Small-Cell Lung - pathology Carnitine Cell growth Cell Line, Tumor Cell proliferation Cell Proliferation - genetics DNA microarrays Energy metabolism fatty acid oxidation Fatty acids Fatty Acids - metabolism Glucose Glucose metabolism Glutaminase Glutamine Glutamine - metabolism Glycolysis Hypoxia Lipid metabolism Lung cancer Lung Neoplasms - pathology Metabolic disorders Metabolism Metabolites Metastases Metastasis Mice Non-small cell lung carcinoma NSCLC Original Oxidation Proteins Tumors
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