Role of miR-181b/Notch1 Axis in circ_TNPO1 Promotion of Proliferation and Migration of Atherosclerotic Vascular Smooth Muscle Cells

Background. The role and expression level change in circ_TNPO1 (hsa_circ_0072951) in atherosclerosis (AS) and VSMC dysfunction remain unknown. In this study, we try to explore the effects of circ_TNPO1 on oxidized low-density lipoprotein (ox-LDL)-induced human vascular smooth muscle cell (VSMC) exce...

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Veröffentlicht in:	Journal of healthcare engineering 2022-03, Vol.2022, p.4086935-12
Hauptverfasser:	Chen, Mingxiang, Li, Fuping, Jiang, Qilong, Zhang, WeiMin, Li, Zhiping, Tang, Wenshuai
Format:	Artikel
Sprache:	eng
Schlagworte:	Atherosclerosis - genetics Atherosclerosis - metabolism beta Karyopherins - metabolism beta Karyopherins - pharmacology Cell Movement - physiology Cell Proliferation Cells, Cultured Humans MicroRNAs - genetics MicroRNAs - metabolism Muscle, Smooth, Vascular - metabolism Receptor, Notch1 - genetics Receptor, Notch1 - metabolism RNA, Circular - genetics Signal Transduction
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