GPER-dependent estrogen signaling increases cardiac GCN5L1 expression

Reversible lysine acetylation regulates the activity of cardiac metabolic enzymes, including those controlling fuel substrate metabolism. Mitochondrial-targeted GCN5L1 and SIRT3 have been shown to regulate the acetylation status of mitochondrial enzymes, but the role that lysine acetylation plays in...

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Veröffentlicht in:American journal of physiology. Heart and circulatory physiology 2022-05, Vol.322 (5), p.H762-H768
Hauptverfasser: Manning, Janet R, Thapa, Dharendra, Zhang, Manling, Stoner, Michael W, Sembrat, John C, Rojas, Mauricio, Scott, Iain
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Sprache:eng
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