TRIMs: Generalists Regulating the NLRP3 Inflammasome Signaling Pathway

Inflammation is a double-edged sword. The moderate inflammatory response is a fundamental defense mechanism produced by the body's resistance to dangerous stimuli and a repair process of the body itself. Increasing studies have confirmed that the overactivation of the inflammasome is involved i...

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Veröffentlicht in:	DNA and cell biology 2022-03, Vol.41 (3), p.262-275
Hauptverfasser:	Deng, Nian-Hua, Zhou, Zhi-Xiang, Liu, Hui-Ting, Tian, Zhen, Wu, Ze-Fan, Liu, Xi-Yan, Xiong, Wen-Hao, Wang, Zuo, Jiang, Zhi-Sheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Inflammasomes Inflammasomes - physiology Inflammation - etiology Inflammation - physiopathology Inflammatory diseases Inflammatory response Models, Biological NLR Family, Pyrin Domain-Containing 3 Protein - physiology Regulatory mechanisms (biology) Reviews Signal transduction Signal Transduction - physiology Tripartite Motif Proteins - physiology Ubiquitination
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