The Relationship of Kidney Tubule Biomarkers with Brain Imaging in CKD Patients in SPRINT

Urine biomarker concentrations reflecting kidney tubule injury and dysfunction were not associated with brain MRI measures.Higher eGFR was associated with lower total brain cerebral blood flow.This is the first evaluation of the relationship of kidney tubule biomarkers with brain imaging by MRI in p...

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Veröffentlicht in:Kidney360 2022-02, Vol.3 (2), p.337-340
Hauptverfasser: Miller, Lindsay M, Kurella Tamura, Manjula, Pajewski, Nicholas M, Rifkin, Dena, Weiner, Daniel, Marquine, Maria, Shlipak, Michael G, Ix, Joachim H
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container_end_page 340
container_issue 2
container_start_page 337
container_title Kidney360
container_volume 3
creator Miller, Lindsay M
Kurella Tamura, Manjula
Pajewski, Nicholas M
Rifkin, Dena
Weiner, Daniel
Marquine, Maria
Shlipak, Michael G
Ix, Joachim H
description Urine biomarker concentrations reflecting kidney tubule injury and dysfunction were not associated with brain MRI measures.Higher eGFR was associated with lower total brain cerebral blood flow.This is the first evaluation of the relationship of kidney tubule biomarkers with brain imaging by MRI in patients with CKD.
doi_str_mv 10.34067/KID.0007702021
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subjects Biomarkers
Brain - diagnostic imaging
Brief Communication
Glomerular Filtration Rate - physiology
Humans
Kidney Tubules - injuries
Neuroimaging
Renal Insufficiency, Chronic - diagnostic imaging
title The Relationship of Kidney Tubule Biomarkers with Brain Imaging in CKD Patients in SPRINT
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