Evidence for H-bonding interactions to the μ-η2:η2-peroxide of oxy-tyrosinase that activate its coupled binuclear copper active site

The factors that control the diverse reactivity of the μ-η 2 :η 2 -peroxo dicopper(II) oxy-intermediates in the coupled binuclear copper proteins remain elusive. Here, spectroscopic and computational methods reveal H-bonding interactions between active-site waters and the μ-η 2 :η 2 -peroxide of oxy...

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Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2022-03, Vol.58 (24), p.3913-3916
Hauptverfasser:	Kipouros, Ioannis, Stańczak, Agnieszka, Culka, Martin, Andris, Erik, Machonkin, Timothy R., Rulíšek, Lubomír, Solomon, Edward I.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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