TSSK3, a novel target for male contraception, is required for spermiogenesis

We have previously shown that members of the family of testis‐specific serine/threonine kinases (TSSKs) are post‐meiotically expressed in testicular germ cells and in mature sperm in mammals. The restricted post‐meiotic expression of TSSKs as well as the importance of phosphorylation in signaling pr...

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Veröffentlicht in:	Molecular reproduction and development 2021-11, Vol.88 (11), p.718-730
Hauptverfasser:	Nayyab, Saman, Gervasi, María G., Tourzani, Darya A., Caraballo, Diego A., Jha, Kula N., Teves, Maria E., Cui, Wei, Georg, Gunda I., Visconti, Pablo E., Salicioni, Ana M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Animals Cell differentiation Contraception Contraceptives CRISPR Epididymis evolution Female fertilization Germ cells intronless gene Juveniles kinases Male Mammals Mating Meiosis Mice Mice, Knockout nonhormonal male contraceptive Phenotypes Phosphorylation Protein Serine-Threonine Kinases - genetics Protein Serine-Threonine Kinases - metabolism Sperm Spermatids spermatogenesis Spermatogenesis - genetics Spermatozoa - metabolism Spermiogenesis Testis - metabolism testis‐specific Threonine TSSK3
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