Pre-existing SARS-CoV-2 immunity influences potency, breadth, and durability of the humoral response to SARS-CoV-2 vaccination

The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic highlights the importance of determining the breadth and durability of humoral immunity to SARS-CoV-2 mRNA vaccination. Herein, we characterize the humoral response in 27 naive and 40 recovered vaccinees. SARS-CoV-2-sp...

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Veröffentlicht in:	Cell reports. Medicine 2022-04, Vol.3 (4), p.100603-100603, Article 100603
Hauptverfasser:	Mantus, Grace, Nyhoff, Lindsay E., Edara, Venkata-Viswanadh, Zarnitsyna, Veronika I., Ciric, Caroline R., Flowers, Maria W., Norwood, Carson, Ellis, Madison, Hussaini, Laila, Manning, Kelly E., Stephens, Kathy, Anderson, Evan J., Ahmed, Rafi, Suthar, Mehul S., Wrammert, Jens
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Viral antibody durability COVID-19 - prevention & control COVID-19 Vaccines Humans humoral response memory B cells mRNA vaccination RBD SARS-CoV-2 SARS-CoV-2 - genetics Vaccination Viral Vaccines
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