Prenatal Δ9-Tetrahydrocannabinol Exposure in Males Leads to Motivational Disturbances Related to Striatal Epigenetic Dysregulation

Cannabis remains one of the most widely abused drugs during pregnancy. In utero exposure to its principal psychoactive component, Δ9-tetrahydrocannabinol (THC), can result in long-term neuropsychiatric risk for the progeny. This study investigated epigenetic signatures underlying these enduring cons...

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Veröffentlicht in:	Biological psychiatry (1969) 2022-07, Vol.92 (2), p.127-138
Hauptverfasser:	Ellis, Randall J., Bara, Anissa, Vargas, Claudia A., Frick, Amy L., Loh, Eddie, Landry, Joseph, Uzamere, Teddy O., Callens, James E., Martin, Qammarah, Rajarajan, Prashanth, Brennand, Kristen, Ramakrishnan, Aarthi, Shen, Li, Szutorisz, Henrietta, Hurd, Yasmin L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cannabis Chromatin Depression Epigenetics Motivation Pregnancy
Online-Zugang:	Volltext
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