Biomaterials as Haemostatic Agents in Cardiovascular Surgery: Review of Current Situation and Future Trends
Intraoperative haemostasis is of paramount importance in the practice of cardiovascular surgery. Over the past 70 years, topical haemostatic methods have advanced significantly and today we deal with various haemostatic agents with different properties and different mechanisms of action. The particu...
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| Veröffentlicht in: | Polymers 2022-03, Vol.14 (6), p.1189 |
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| creator | Moldovan, Horațiu Antoniac, Iulian Gheorghiță, Daniela Safta, Maria Sabina Preda, Silvia Broască, Marian Badilă, Elisabeta Fronea, Oana Scafa-Udrişte, Alexandru Cacoveanu, Mihai Molnar, Adrian Costache, Victor Sebastian Zaharia, Ondin |
| description | Intraoperative haemostasis is of paramount importance in the practice of cardiovascular surgery. Over the past 70 years, topical haemostatic methods have advanced significantly and today we deal with various haemostatic agents with different properties and different mechanisms of action. The particularity of coagulation mechanisms after extracorporeal circulation, has encouraged the introduction of new types of topic agents to achieve haemostasis, where conventional methods prove their limits. These products have an important role in cardiac, as well as in vascular, surgery, mainly in major vascular procedures, like aortic dissections and aortic aneurysms. This article presents those agents used for topical application and the mechanism of haemostasis and offers general recommendations for their use in the operating room. |
| doi_str_mv | 10.3390/polym14061189 |
| format | Article |
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Over the past 70 years, topical haemostatic methods have advanced significantly and today we deal with various haemostatic agents with different properties and different mechanisms of action. The particularity of coagulation mechanisms after extracorporeal circulation, has encouraged the introduction of new types of topic agents to achieve haemostasis, where conventional methods prove their limits. These products have an important role in cardiac, as well as in vascular, surgery, mainly in major vascular procedures, like aortic dissections and aortic aneurysms. This article presents those agents used for topical application and the mechanism of haemostasis and offers general recommendations for their use in the operating room.</description><identifier>ISSN: 2073-4360</identifier><identifier>EISSN: 2073-4360</identifier><identifier>DOI: 10.3390/polym14061189</identifier><identifier>PMID: 35335519</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Aorta ; Biomedical materials ; Blood platelets ; Blood products ; Blood transfusions ; Cardiovascular disease ; Coagulation ; Heart surgery ; Hypothermia ; Mortality ; Patients ; Review ; Sealing compounds ; Surgeons ; Surgery ; Sutures</subject><ispartof>Polymers, 2022-03, Vol.14 (6), p.1189</ispartof><rights>2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). 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| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central Open Access; MDPI - Multidisciplinary Digital Publishing Institute; PubMed Central |
| subjects | Aorta Biomedical materials Blood platelets Blood products Blood transfusions Cardiovascular disease Coagulation Heart surgery Hypothermia Mortality Patients Review Sealing compounds Surgeons Surgery Sutures |
| title | Biomaterials as Haemostatic Agents in Cardiovascular Surgery: Review of Current Situation and Future Trends |
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