Thioredoxin 1 (Trx1) is associated with poor prognosis in clear cell renal cell carcinoma (ccRCC): an example for the crucial role of redox signaling in ccRCC

Purpose Thioredoxins are major regulatory proteins of oxidative signaling. Trx1 is the most prominent thioredoxin and, therefore, the current study sought to evaluate the prognostic role of Trx1 in ccRCC. Methods and patients A tissue micro-array (TMA) study was carried out to evaluate the associati...

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Veröffentlicht in:	World journal of urology 2022-03, Vol.40 (3), p.739-746
Hauptverfasser:	Ribback, Silvia, Winter, Stefan, Klatte, Tobias, Schaeffeler, Elke, Gellert, Manuela, Stühler, Viktoria, Scharpf, Marcus, Bedke, Jens, Burchardt, Martin, Schwab, Matthias, Lillig, Christopher H., Kroeger, Nils
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers, Tumor - metabolism Carcinoma, Renal Cell - diagnosis Carcinoma, Renal Cell - pathology Clear cell-type renal cell carcinoma Copy number Cytoplasm DNA Copy Number Variations Humans Kidney cancer Kidney Neoplasms - diagnosis Kidney Neoplasms - pathology Medical prognosis Medicine Medicine & Public Health Metastases Nephrology Oncology Original Original Article Oxidation-Reduction Prognosis Regulatory proteins Thioredoxin Thioredoxins - genetics Thioredoxins - metabolism Tumors Urology
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