In vitro activities of Strychnos alkaloids and extracts against Plasmodium falciparum

The in vitro antimalarial activities of 46 alkaloids and extracts from Strychnos species were evaluated. Two types of quasidimeric alkaloids exhibit high and selective activities against Plasmodium. Strychnopentamine and isostrychnopentamine were active against chloroquine-sensitive and -resistant s...

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Veröffentlicht in:Antimicrobial agents and chemotherapy 1999-09, Vol.43 (9), p.2328-2331
Hauptverfasser: FREDERICH, M, HAYETTE, M.-P, TITS, M, DE MOL, P, ANGENOT, L
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Sprache:eng
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