MitoQ Inhibits Human Breast Cancer Cell Migration, Invasion and Clonogenicity

To successfully generate distant metastases, metastatic progenitor cells must simultaneously possess mesenchymal characteristics, resist to anoïkis, migrate and invade directionally, resist to redox and shear stresses in the systemic circulation, and possess stem cell characteristics. These cells pr...

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Veröffentlicht in:	Cancers 2022-03, Vol.14 (6), p.1516
Hauptverfasser:	Capeloa, Tania, Krzystyniak, Joanna, d'Hose, Donatienne, Canas Rodriguez, Amanda, Payen, Valery L, Zampieri, Luca X, Van de Velde, Justine A, Benyahia, Zohra, Pranzini, Erica, Vazeille, Thibaut, Fransolet, Maude, Bouzin, Caroline, Brusa, Davide, Michiels, Carine, Gallez, Bernard, Murphy, Michael P, Porporato, Paolo E, Sonveaux, Pierre
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants Breast cancer Cell adhesion & migration Cell culture Cell cycle Cell migration Clinical trials Drug dosages ErbB-2 protein Focal adhesion kinase Growth factors Hypoxia Intracellular signalling Invasiveness Mesenchyme Metabolism Metastases Metastasis Microenvironments Mitochondria Phenotypes Progenitor cells Solid tumors Stem cells Superoxide Transforming growth factor-b Tumor cell lines Tumors
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