Effect of metal ions on Alzheimer's disease

Alzheimer's disease (AD) is a degenerative disease of the nervous system. The typical pathological changes of AD are Aβ deposition, neurofibrillary tangles, neuron loss, and chronic inflammation. The balance of metal ions is essential for numerous physiological functions, especially in the cent...

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Veröffentlicht in:	Brain and behavior 2022-03, Vol.12 (3), p.e2527-n/a
Hauptverfasser:	Liu, Fan, Zhang, Zhuo, Zhang, Lin, Meng, Ruo‐Ni, Gao, Jia, Jin, Ming, Li, Ming, Wang, Xiao‐Peng
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - pathology Alzheimer's disease Amyloid beta-Peptides Apoptosis CNS Cyclin-dependent kinases Dementia Free radicals Humans Inflammation Ions Kinases Metabolism metal ions Metals mild cognitive impairment neurological diseases Neurotoxicity Oxidative stress Pathogenesis Pathology Physiology Proteins Respiration Review Reviews the central nervous system Tumor necrosis factor-TNF
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