Cohorts and consortia conference: a summary report (Banff, Canada, June 17-19, 2009)
Epidemiologic studies have adapted to the genomics era by forming large international consortia to overcome issues of large data volume and small sample size. Whereas both cohort and well-conducted case-control studies can inform disease risk from genetic susceptibility, cohort studies offer the add...
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Veröffentlicht in: | Cancer causes & control 2011-03, Vol.22 (3), p.463-468 |
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creator | Boffetta, Paolo Colditz, Graham A Potter, John D Kolonel, Laurence Robson, Paula J Malekzadeh, Reza Seminara, Daniela Goode, Ellen L Yoo, Keun-Young Demers, Paul Gallagher, Richard Prentice, Ross Yasui, Yutaka O'Doherty, Kieran Petersen, Gloria M Ulrich, Cornelia M Csizmadi, Ilona Amankwah, Ernest K Brockton, Nigel T Kopciuk, Karen McGregor, S. Elizabeth Kelemen, Linda E |
description | Epidemiologic studies have adapted to the genomics era by forming large international consortia to overcome issues of large data volume and small sample size. Whereas both cohort and well-conducted case-control studies can inform disease risk from genetic susceptibility, cohort studies offer the additional advantages of assessing lifestyle and environmental exposure-disease time sequences often over a life course. Consortium involvement poses several logistical and ethical issues to investigators, some of which are unique to cohort studies, including the challenge to harmonize prospectively collected lifestyle and environmental exposures validly across individual studies. An open forum to discuss the opportunities and challenges of large-scale cohorts and their consortia was held in June 2009 in Banff, Canada, and is summarized in this report. |
doi_str_mv | 10.1007/s10552-010-9717-0 |
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Elizabeth</creatorcontrib><creatorcontrib>Kelemen, Linda E</creatorcontrib><title>Cohorts and consortia conference: a summary report (Banff, Canada, June 17-19, 2009)</title><title>Cancer causes & control</title><addtitle>Cancer Causes Control</addtitle><addtitle>Cancer Causes Control</addtitle><description>Epidemiologic studies have adapted to the genomics era by forming large international consortia to overcome issues of large data volume and small sample size. Whereas both cohort and well-conducted case-control studies can inform disease risk from genetic susceptibility, cohort studies offer the additional advantages of assessing lifestyle and environmental exposure-disease time sequences often over a life course. Consortium involvement poses several logistical and ethical issues to investigators, some of which are unique to cohort studies, including the challenge to harmonize prospectively collected lifestyle and environmental exposures validly across individual studies. 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subjects | Biobanks Biological specimen banks Biomedical and Life Sciences Biomedicine Canada Cancer Cancer Research Case-Control Studies Childhood Clinical Trials as Topic - methods Cohort analysis Cohort Studies Conferences Consortia Data harmonization Design Environmental Exposure - analysis Epidemiology ethics Etiology Funding Genomics Health care Health sciences Hematology Humans Lifestyles Medical research molecular epidemiology neoplasms Oncology Original Paper Preventive medicine Prospective studies Public Health Research centers Research facilities Research Report Risk Assessment - methods Sample Size |
title | Cohorts and consortia conference: a summary report (Banff, Canada, June 17-19, 2009) |
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