Cohorts and consortia conference: a summary report (Banff, Canada, June 17-19, 2009)

Epidemiologic studies have adapted to the genomics era by forming large international consortia to overcome issues of large data volume and small sample size. Whereas both cohort and well-conducted case-control studies can inform disease risk from genetic susceptibility, cohort studies offer the add...

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Veröffentlicht in:Cancer causes & control 2011-03, Vol.22 (3), p.463-468
Hauptverfasser: Boffetta, Paolo, Colditz, Graham A, Potter, John D, Kolonel, Laurence, Robson, Paula J, Malekzadeh, Reza, Seminara, Daniela, Goode, Ellen L, Yoo, Keun-Young, Demers, Paul, Gallagher, Richard, Prentice, Ross, Yasui, Yutaka, O'Doherty, Kieran, Petersen, Gloria M, Ulrich, Cornelia M, Csizmadi, Ilona, Amankwah, Ernest K, Brockton, Nigel T, Kopciuk, Karen, McGregor, S. Elizabeth, Kelemen, Linda E
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container_end_page 468
container_issue 3
container_start_page 463
container_title Cancer causes & control
container_volume 22
creator Boffetta, Paolo
Colditz, Graham A
Potter, John D
Kolonel, Laurence
Robson, Paula J
Malekzadeh, Reza
Seminara, Daniela
Goode, Ellen L
Yoo, Keun-Young
Demers, Paul
Gallagher, Richard
Prentice, Ross
Yasui, Yutaka
O'Doherty, Kieran
Petersen, Gloria M
Ulrich, Cornelia M
Csizmadi, Ilona
Amankwah, Ernest K
Brockton, Nigel T
Kopciuk, Karen
McGregor, S. Elizabeth
Kelemen, Linda E
description Epidemiologic studies have adapted to the genomics era by forming large international consortia to overcome issues of large data volume and small sample size. Whereas both cohort and well-conducted case-control studies can inform disease risk from genetic susceptibility, cohort studies offer the additional advantages of assessing lifestyle and environmental exposure-disease time sequences often over a life course. Consortium involvement poses several logistical and ethical issues to investigators, some of which are unique to cohort studies, including the challenge to harmonize prospectively collected lifestyle and environmental exposures validly across individual studies. An open forum to discuss the opportunities and challenges of large-scale cohorts and their consortia was held in June 2009 in Banff, Canada, and is summarized in this report.
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source MEDLINE; SpringerNature Journals; JSTOR Archive Collection A-Z Listing
subjects Biobanks
Biological specimen banks
Biomedical and Life Sciences
Biomedicine
Canada
Cancer
Cancer Research
Case-Control Studies
Childhood
Clinical Trials as Topic - methods
Cohort analysis
Cohort Studies
Conferences
Consortia
Data harmonization
Design
Environmental Exposure - analysis
Epidemiology
ethics
Etiology
Funding
Genomics
Health care
Health sciences
Hematology
Humans
Lifestyles
Medical research
molecular epidemiology
neoplasms
Oncology
Original Paper
Preventive medicine
Prospective studies
Public Health
Research centers
Research facilities
Research Report
Risk Assessment - methods
Sample Size
title Cohorts and consortia conference: a summary report (Banff, Canada, June 17-19, 2009)
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