The Novel Nrf2 Activator Omaveloxolone Regulates Microglia Phenotype and Ameliorates Secondary Brain Injury after Intracerebral Hemorrhage in Mice

The polarization of microglia is recognized as a crucial factor in reducing neuroinflammation and promoting hematoma clearance after intracerebral hemorrhage (ICH). Previous studies have revealed that redox components participate in the regulation of microglial polarization. Recently, the novel Nrf2...

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Veröffentlicht in:	Oxidative medicine and cellular longevity 2022, Vol.2022, p.4564471-18
Hauptverfasser:	Hu, Libin, Cao, Yang, Chen, Huaijun, Xu, Lei, Yang, Qiguo, Zhou, Hang, Li, Jianru, Yu, Qian, Dou, Zhangqi, Li, Yin, Yan, Feng, Liu, Fuyi, Chen, Gao
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants Cell culture Clinical trials Drug dosages Experiments Hematoma Laboratory animals Traumatic brain injury
Online-Zugang:	Volltext
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