Integrated Analysis of Ulcerative Colitis Revealed an Association between PHLPP2 and Immune Infiltration

Ulcerative colitis (UC) is a progressive intestine inflammatory disease that is prone to recur. Herein, we utilize microarray technology and bioinformatics to reveal the underlying pathogenesis of UC and provide novel markers. Colonic biopsies were taken from eight UC patients and eight healthy cont...

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Veröffentlicht in:	Disease markers 2022, Vol.2022, p.4983471-15
Hauptverfasser:	Li, Ting, Liu, Weidong, Hui, Wenjia, Shi, Tian, Liu, Huan, Feng, Yan, Gao, Feng
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Bioinformatics Biomarkers Biomarkers - metabolism Biopsy Colitis, Ulcerative - genetics Colitis, Ulcerative - immunology Colitis, Ulcerative - pathology Colon - immunology Colon - pathology Computational Biology Correlation analysis Cytokines Datasets Disease Down-Regulation Epithelial-Mesenchymal Transition Extracellular matrix Gene expression Gene Expression Profiling Genes Humans Immune response Immune system Inflammatory bowel disease Inflammatory bowel diseases Interleukin 17 Interleukin-17 - immunology Intestine Lymphocytes Lymphocytes T Macrophages Mast cells Mesenchyme MicroRNAs MicroRNAs - genetics miRNA mRNA Ontology Pathogenesis Phosphoprotein Phosphatases - metabolism RNA, Messenger - genetics Signal transduction Software Ulcerative colitis
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