The Error-Prone Polymerase DnaE2 Mediates the Evolution of Antibiotic Resistance in Persister Mycobacterial Cells

Applying antibiotics to susceptible bacterial cultures generates a minor population of persisters that remain susceptible to antibiotics but can endure them for extended periods. Recent reports suggest that antibiotic persisters (APs) of mycobacteria experience oxidative stress and develop resistanc...

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Veröffentlicht in:	Antimicrobial agents and chemotherapy 2022-03, Vol.66 (3), p.e0177321-e0177321
Hauptverfasser:	Salini, S, Bhat, Sinchana G, Naz, Saba, Natesh, Ramanathan, Kumar, R Ajay, Nandicoori, Vinay Kumar, Kurthkoti, Krishna
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Antimicrobial Chemotherapy Ciprofloxacin - pharmacology Drug Resistance, Bacterial - genetics Mechanisms of Resistance Mycobacterium tuberculosis - genetics Rifampin - pharmacology
Online-Zugang:	Volltext
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