A Novel Malaria Lateral Flow Assay for Detecting Plasmodium falciparum Lactate Dehydrogenase in Busia, Uganda

Rapid diagnostic tests (RDTs) for Plasmodium falciparum commonly detect histidine-rich protein 2 (HRP-2), but HRP-2 deletions are increasingly recognized. We evaluated a prototype test detecting parasite lactate dehydrogenase (pLDH) and compared it to commercially available RDTs at a health facility...

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Veröffentlicht in:	The American journal of tropical medicine and hygiene 2022-01, Vol.106 (3), p.850-852
Hauptverfasser:	Bachman, Christine M, Cate, David M, Grant, Ben, Burkot, Stephen, Mulondo, Jerry, Hsieh, Helen V, Chamai, Martin, Odongo, Bakar, Olwoch, Peter, Nalubega, Mayimuna, Ochokoru, Harriet, Kasozi, Joseph, Ategeka, John, Nichols, Kevin P, Weigl, Bernhard H, Greenhouse, Bryan
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, Protozoan - analysis Dehydrogenases Diagnostic Tests, Routine Erythrocytes Humans L-Lactate Dehydrogenase - analysis Malaria Malaria - diagnosis Malaria, Falciparum - diagnosis Malaria, Falciparum - parasitology Microscopy Plasmodium falciparum Polymerase Chain Reaction Protozoan Proteins - genetics Protozoan Proteins - metabolism Sensitivity and Specificity Short Report Uganda
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