Case Report: Local Treatment of a Leishmania tropica Infection in a Syrian Child with a Novel Filmogenic Preparation of Pharmaceutical Sodium Chlorite (LeiProtect®)
Cutaneous leishmaniasis (CL) frequently entails chronic skin lesions that heal only slowly. Until now, the available therapeutic options are very limited. Here, we present a case of a 5½-year-old Syrian refugee with two progressive lower-leg skin ulcers caused by Leishmania tropica. The patient rece...
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| Veröffentlicht in: | The American journal of tropical medicine and hygiene 2022-03, Vol.106 (3), p.857-860 |
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| container_title | The American journal of tropical medicine and hygiene |
| container_volume | 106 |
| creator | Debus, Dirk Genç, Semra Kurz, Philipp Holzer, Martin Bauer, Kurt Heimke-Brinck, Ralph Baier, Martin Sebald, Heidi Debus, Andrea Bogdan, Christian Stahl, Kurt-Wilhelm |
| description | Cutaneous leishmaniasis (CL) frequently entails chronic skin lesions that heal only slowly. Until now, the available therapeutic options are very limited. Here, we present a case of a 5½-year-old Syrian refugee with two progressive lower-leg skin ulcers caused by Leishmania tropica. The patient received topical treatment with LeiProtect®, a newly developed, hydroxypropylcellulose-based, filmogenic gel containing nontoxic concentrations of pharmaceutical sodium chlorite. The skin lesions completely healed within 8 weeks and did not relapse during 1 year of follow-up, underlining the efficacy of this novel local therapy of CL. |
| doi_str_mv | 10.4269/ajtmh.21-0962 |
| format | Article |
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Until now, the available therapeutic options are very limited. Here, we present a case of a 5½-year-old Syrian refugee with two progressive lower-leg skin ulcers caused by Leishmania tropica. The patient received topical treatment with LeiProtect®, a newly developed, hydroxypropylcellulose-based, filmogenic gel containing nontoxic concentrations of pharmaceutical sodium chlorite. 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The skin lesions completely healed within 8 weeks and did not relapse during 1 year of follow-up, underlining the efficacy of this novel local therapy of CL.</description><subject>Case Report</subject><subject>Case reports</subject><subject>Child</subject><subject>Children & youth</subject><subject>Chlorides</subject><subject>Drug therapy</subject><subject>Humans</subject><subject>Leishmania tropica</subject><subject>Leishmaniasis, Cutaneous - drug therapy</subject><subject>Medical treatment</subject><subject>Middle Aged</subject><subject>Parasites</subject><subject>Parasitic diseases</subject><subject>Pharmaceutical Preparations</subject><subject>Syria</subject><issn>0002-9637</issn><issn>1476-1645</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkctu1DAUhi0EokNhyRZZYlMWaX1JnJgFUjWiUGlURrSsrRNfGo-SODhOUR-ILQ_Bk-FpSwUrS_bn7z86P0KvKTkumZAnsEtDd8xoQaRgT9CKlrUoqCirp2hFCGGFFLw-QC_meUcIbRilz9EBrwhpiKAr9HMNs8Vf7RRieo83QUOPr6KFNNgx4eAw4I31czfA6AGnGCavAZ-Pzurkw4j9mInL2-hhxOvO9wb_8KnLdxfhxvb4zPdDuLaj13gb7QQR7n5l77aDOIC2S_L7zMtg_DJkRR-iTxYf5dRtDCnH_P717iV65qCf7auH8xB9O_t4tf5cbL58Ol-fbgrNeZOKqubgONfGSe7airack5pTINI1VhpZOypL1-iqcUYbTXllWl5bqFsjgTvgh-jDvXda2sEanXcQoVdT9APEWxXAq_9fRt-p63CjGslY2YgsePsgiOH7YuekdmGJY55ZMVGyqhSslJkq7ikdwzxH6x4TKFH7VtVdq4pRtW8182_-HeuR_lsj_wPuuaMh</recordid><startdate>20220301</startdate><enddate>20220301</enddate><creator>Debus, Dirk</creator><creator>Genç, Semra</creator><creator>Kurz, Philipp</creator><creator>Holzer, Martin</creator><creator>Bauer, Kurt</creator><creator>Heimke-Brinck, Ralph</creator><creator>Baier, Martin</creator><creator>Sebald, Heidi</creator><creator>Debus, Andrea</creator><creator>Bogdan, Christian</creator><creator>Stahl, Kurt-Wilhelm</creator><general>Institute of Tropical Medicine</general><general>The American Society of Tropical Medicine and Hygiene</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>5PM</scope></search><sort><creationdate>20220301</creationdate><title>Case Report: Local Treatment of a Leishmania tropica Infection in a Syrian Child with a Novel Filmogenic Preparation of Pharmaceutical Sodium Chlorite (LeiProtect®)</title><author>Debus, Dirk ; 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| subjects | Case Report Case reports Child Children & youth Chlorides Drug therapy Humans Leishmania tropica Leishmaniasis, Cutaneous - drug therapy Medical treatment Middle Aged Parasites Parasitic diseases Pharmaceutical Preparations Syria |
| title | Case Report: Local Treatment of a Leishmania tropica Infection in a Syrian Child with a Novel Filmogenic Preparation of Pharmaceutical Sodium Chlorite (LeiProtect®) |
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