Targeted ablation of gastric pacemaker sites to modulate patterns of bioelectrical slow wave activation and propagation in an anesthetized pig model

Gastric motility is coordinated by underlying bioelectrical slow waves. Gastric dysrhythmias occur in gastrointestinal (GI) motility disorders, but there are no validated methods for eliminating dysrhythmias. We hypothesized that targeted ablation could eliminate pacemaker sites in the stomach, incl...

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Veröffentlicht in:	American journal of physiology: Gastrointestinal and liver physiology 2022-04, Vol.322 (4), p.G431-G445
Hauptverfasser:	Aghababaie, Zahra, Cheng, Leo K, Paskaranandavadivel, Niranchan, Avci, Recep, Chan, Chih-Hsiang Alexander, Matthee, Ashton, Amirapu, Satya, Asirvatham, Samuel J, Farrugia, Gianrico, Beyder, Arthur, O'Grady, Gregory, Angeli-Gordon, Timothy R
Format:	Artikel
Sprache:	eng
Schlagworte:	Ablation Animals Catheter Ablation Gastric motility Gastrointestinal Diseases Gastrointestinal Motility - physiology Interstitial Cells of Cajal - physiology Mapping Motility Nervous system Pacemakers Radiofrequency ablation Serous Membrane Stomach - physiology Swine
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