The role of neutrophils in host defense and disease

Neutrophils, the most abundant circulating leukocyte, are critical for host defense. Granulopoiesis is under the control of transcriptional factors and culminates in mature neutrophils with a broad armamentarium of antimicrobial pathways. These pathways include nicotinamide adenine dinucleotide phos...

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Veröffentlicht in:	Journal of allergy and clinical immunology 2020-06, Vol.145 (6), p.1535-1544
Hauptverfasser:	Lehman, Heather K., Segal, Brahm H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Plasticity - immunology degranulation granulopoiesis Humans Infections - immunology Inflammation - immunology innate immunity Neoplasms - immunology neutrophil dysfunction neutrophil extracellular traps Neutrophils Neutrophils - immunology phagocytosis Tumor Microenvironment - immunology
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