Evaluation of Myeloperoxidase as Target for Host-Directed Therapy in Tuberculosis In Vivo

Due to the rise of tuberculosis cases infected with multi and extensively drug-resistant strains and the emergence of isolates resistant to antibiotics newly in clinical use, host-directed therapies targeting pathogenesis-associated immune pathways adjunct to antibiotics may ameliorate disease and b...

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Veröffentlicht in:	International journal of molecular sciences 2022-02, Vol.23 (5), p.2554
Hauptverfasser:	Linnemann, Lara C, Schaible, Ulrich E, Dallenga, Tobias K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Animals Anti-Bacterial Agents - therapeutic use Antibiotics Apoptosis Cytokines Disease Models, Animal Drug resistance Health services Immune clearance Immune system Infections Isoniazid Leukocytes (neutrophilic) Lungs Lymphocytes Macrophages Mice Mice, Inbred Strains Mycobacterium tuberculosis Necrosis Necrosis - pathology Neutrophils Pathogenesis Pathology Peroxidase Tuberculosis Tuberculosis - microbiology
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